唐氏综合征中多发性骨髓瘤的罕见表现及治疗挑战：一例病例报告及文献综述
A rare presentation and treatment challenges for multiple myeloma in down syndrome: A case report and literature review.
作者信息
Musleh Mais, Alhusein Qossay
机构信息
Department of Hematology Faculty of Medicine, Al Assad University Hospital Damascus Syria.
Department of Hematology Faculty of Medicine, Al-Mouwasat University Hospital Damascus Syria.
出版信息
Clin Case Rep. 2024 Jul 3;12(7):e9154. doi: 10.1002/ccr3.9154. eCollection 2024 Jul.
Down syndrome (DS), characterized by trisomy 21, significantly increases susceptibility to leukemia, although the occurrence of multiple myeloma (MM) in DS is exceedingly rare. This report details the case of a 45-year-old female with DS who was diagnosed with MM, highlighting diagnostic and therapeutic complexities. It emphasizes the importance of tailored therapeutic strategies for treating MM in individuals with DS and the need for specialized approaches in these cases.
唐氏综合征（DS），其特征为21号染色体三体，会显著增加患白血病的易感性，尽管DS患者中多发性骨髓瘤（MM）的发生极为罕见。本报告详细介绍了一名45岁患有DS的女性被诊断为MM的病例，突出了诊断和治疗的复杂性。它强调了为DS患者制定个性化MM治疗策略的重要性以及在这些病例中采用专门方法的必要性。
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