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抗逆转录病毒药物治疗 HIV 感染的具体情况。

SPECIFICS OF PRESCRIBING ANTIRETROVIRAL DRUGS IN THE TREATMENT OF HIV INFECTION.

机构信息

NWSMU named after I.I. Mechnikov, Saint-Petersburg, Russia.

出版信息

Georgian Med News. 2024 Apr(349):149-153.

Abstract

HIV infection is one of the most acute problems of our time, characterized by slow development, prolonged course, and numerous clinical manifestations. Currently, there is a large number of drugs acting on different processes of human immunodeficiency virus replication, which constitute the group of highly active antiretroviral therapy (HAART). This article shows a theoretical review of modern HAART and analyzes the prescribed treatment regimens for patients with HIV infection. The study revealed two most common combinations: nucleoside reverse transcriptase inhibitors + protease inhibitors; nucleoside + non-nucleoside reverse transcriptase inhibitors.

摘要

HIV 感染是我们这个时代最严重的问题之一,其特点是发展缓慢、病程长、临床表现多样。目前,有大量作用于人类免疫缺陷病毒复制不同过程的药物,这些药物构成了高效抗逆转录病毒治疗(HAART)的药物。本文对现代 HAART 进行了理论综述,并分析了 HIV 感染患者的规定治疗方案。研究揭示了两种最常见的组合:核苷逆转录酶抑制剂+蛋白酶抑制剂;核苷+非核苷逆转录酶抑制剂。

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