University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA.
University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
Curr Cardiol Rep. 2024 Aug;26(8):843-849. doi: 10.1007/s11886-024-02084-9. Epub 2024 Jul 4.
Acute pulmonary embolism (PE) is a leading cause of cardiovascular death and morbidity, and presents a major burden to healthcare systems. The field has seen rapid growth with development of innovative clot reduction technologies, as well as ongoing multicenter trials that may completely revolutionize care of PE patients. However, current paucity of robust clinical trials and guidelines often leave individual physicians managing patients with acute PE in a dilemma.
The pulmonary embolism response team (PERT) was developed as a platform to rapidly engage multiple specialists to deliver evidence-based, organized and efficient care and help address some of the gaps in knowledge. Several centers investigating outcomes following implementation of PERT have demonstrated shorter hospital and intensive-care unit stays, lower use of inferior vena cava filters, and in some instances improved mortality. Since the advent of PERT, early findings demonstrate promise with improved outcomes after implementation of PERT. Incorporation of artificial intelligence (AI) into PERT has also shown promise with more streamlined care and reducing response times. Further clinical trials are needed to examine the impact of PERT model on care delivery and clinical outcomes.
急性肺栓塞(PE)是心血管死亡和发病的主要原因,给医疗系统带来了巨大负担。随着创新性血栓清除技术的发展,以及可能彻底改变 PE 患者治疗的正在进行的多中心试验,该领域取得了快速进展。然而,目前缺乏强有力的临床试验和指南,这使得个别医生在管理急性 PE 患者时陷入困境。
肺栓塞反应小组(PERT)的建立是为了快速召集多个专家提供基于证据的、有组织的和高效的护理,并帮助解决一些知识上的差距。一些中心调查了实施 PERT 后的结果,发现住院时间和重症监护病房停留时间缩短,下腔静脉滤器的使用减少,在某些情况下死亡率降低。自 PERT 问世以来,早期发现表明实施 PERT 后可改善预后。将人工智能(AI)纳入 PERT 也显示出有希望的前景,可实现更精简的护理和缩短响应时间。需要进一步的临床试验来检查 PERT 模型对护理提供和临床结果的影响。