人肾素的结构分析
A structural analysis of human renin.
作者信息
Morris B J, Guss J M, Hunter W N, Catanzaro D F
出版信息
Clin Exp Pharmacol Physiol. 1985 May-Jun;12(3):299-304. doi: 10.1111/j.1440-1681.1985.tb02649.x.
Abstract
A three-dimensional model of human renin has been used to define amino acid residues involved in interaction with substrate. The structure revealed proteolytic cleavage sites on the surface of the molecule that may help explain numerous experimental observations concerning prorenin and its activation and forms of renin differing in size.
摘要
人类肾素的三维模型已被用于确定与底物相互作用的氨基酸残基。该结构揭示了分子表面的蛋白水解切割位点，这可能有助于解释许多关于肾素原及其激活以及不同大小的肾素形式的实验观察结果。
Zotero 插件