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龋齿罗氏菌性心内膜炎合并脑脓肿和脾脓肿:病例报告及简要综述

Rothia dentocariosa endocarditis with brain abscess and splenic abscess: case report and brief review.

作者信息

Zheng Xue, Liu Fang, Ma Qiaoli, Li Jing, Ma Huiping

机构信息

Clinical Pharmacy, Binzhou Medical University Affiliated Zibo Central Hospital, Zibo, Shandong, China.

Clinical Pharmacy, Shengli Oilfield Central Hospital, Dongying, Shandong, China.

出版信息

Front Cardiovasc Med. 2024 Jun 20;11:1370736. doi: 10.3389/fcvm.2024.1370736. eCollection 2024.

Abstract

Rothia dentocariosa is a conditionally pathogenic bacterium that may cause infective endocarditis (IE) in selected patients and give rise to a variety of clinical complications, albeit it is not a common IE pathogen. We present the case of a patient diagnosed with Rothia dentocariosa-associated IE secondary to influenza B and thrombocytopenic purpura. The blood culture revealed Rochebacterium caries, cardiac ultrasound detected vegetation, while brain and spleen abscesses manifested and progressively deteriorated. Despite a suboptimal response to anti-infective therapy, the patient ultimately underwent aortic valve replacement. Discharge from the hospital was achieved upon control of the brain abscess and spleen abscess.

摘要

龋齿罗氏菌是一种条件致病菌,在特定患者中可能导致感染性心内膜炎(IE)并引发多种临床并发症,尽管它并非常见的IE病原体。我们报告一例继发于乙型流感和血小板减少性紫癜的龋齿罗氏菌相关性IE患者。血培养发现龋齿罗氏菌,心脏超声检测到赘生物,同时出现脑脓肿和脾脓肿且病情逐渐恶化。尽管抗感染治疗反应欠佳,但患者最终接受了主动脉瓣置换术。脑脓肿和脾脓肿得到控制后患者出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/444a/11222609/044352cb18f1/fcvm-11-1370736-g001.jpg

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