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预测儿科创伤患者的严重结局:休克指数儿科年龄校正与年龄校正心动过速。

Predicting severe outcomes in pediatric trauma patients: Shock index pediatric age-adjusted vs. age-adjusted tachycardia.

机构信息

Eli Lilly and Company, 893 Delaware St., Indianapolis, IN 46225, USA.

Marian University College of Osteopathic Medicine, Indianapolis, IN, USA.

出版信息

Am J Emerg Med. 2024 Sep;83:59-63. doi: 10.1016/j.ajem.2024.06.041. Epub 2024 Jul 1.

Abstract

INTRODUCTION

When an injured patient arrives in the Emergency Department (ED), timely and appropriate care is crucial. Shock Index Pediatric Age-Adjusted (SIPA) has been shown to accurately identify pediatric patients in need of emergency interventions. However, no study has evaluated SIPA against age-adjusted tachycardia (AT). This study aims to compare SIPA with AT in predicting outcomes such as mortality, severe injury, and the need for emergent intervention in pediatric trauma patients.

MATERIAL AND METHODS

This is a retrospective cross-sectional analysis of patient data abstracted from the Trauma Quality Improvement Program Participant Use Files (TQIP PUFs) for years 2013-2020. Patients aged 4-16 with blunt mechanism of injury and injury severity score (ISS) > 15 were included. 36,517 children met this criteria. Sensitivity, specificity, overtriage, and undertriage rates were calculated to compare the effectiveness of AT and elevated SIPA as predictors of severe injuries and need for emergent intervention. Emergent interventions included craniotomy, endotracheal intubation, thoracotomy, laparotomy, or chest tube placement within 24 h of arrival.

RESULTS

AT classified 59% of patients as "high risk," while elevated SIPA identified 26%. Compared to AT patients, a greater proportion of patients with elevated SIPA required a blood transfusion within 24 h (22% vs. 12%, respectively; p < 0.001). In-hospital mortality was higher for the elevated SIPA group than AT (10% vs. 5%, respectively; p < 0.001) as well as the need for emergent operative interventions (43% vs. 32% respectively; p < 0.001). Grade 3 or higher liver/spleen lacerations requiring blood transfusion were also more common among elevated SIPA patients than AT patients (8% vs. 4%, respectively; p < 0.001). AT demonstrated greater sensitivity but lower specificity compared to SIPA across all outcomes. AT showed improved overtriage and undertriage rates compared to SIPA, but this is attributed to identifying a large proportion of the sample as "high risk."

CONCLUSIONS

AT outperforms SIPA in sensitivity for mortality, injury severity and emergent interventions in pediatric trauma patients while the specificity of SIPA is high across these outcomes.

摘要

简介

当受伤患者到达急诊部(ED)时,及时和适当的护理至关重要。休克指数儿科年龄调整(SIPA)已被证明可准确识别需要紧急干预的儿科患者。然而,尚无研究将 SIPA 与年龄调整性心动过速(AT)进行比较。本研究旨在比较 SIPA 与 AT 在预测儿科创伤患者的死亡率、严重损伤和紧急干预需求等结局方面的效果。

材料与方法

这是一项回顾性的病例交叉分析,从创伤质量改进计划参与者使用文件(TQIP PUFs)中提取 2013 年至 2020 年的患者数据。纳入年龄为 4-16 岁、钝性损伤机制和损伤严重程度评分(ISS)>15 的患者。符合此标准的 36517 名儿童。计算敏感性、特异性、过度分诊和分诊不足率,以比较 AT 和升高的 SIPA 作为严重损伤和紧急干预需求预测因子的效果。紧急干预包括入院后 24 小时内进行开颅术、气管插管、剖胸术、剖腹术或放置胸腔引流管。

结果

AT 将 59%的患者归类为“高危”,而升高的 SIPA 则识别出 26%的患者。与 AT 患者相比,升高的 SIPA 患者在 24 小时内需要输血的比例更高(分别为 22%和 12%;p<0.001)。升高的 SIPA 组的院内死亡率高于 AT 组(分别为 10%和 5%;p<0.001),以及需要紧急手术干预的比例也更高(分别为 43%和 32%;p<0.001)。需要输血的 3 级或更高级别的肝/脾撕裂伤在升高的 SIPA 患者中也比 AT 患者更常见(分别为 8%和 4%;p<0.001)。

结论

与 SIPA 相比,AT 在预测儿科创伤患者的死亡率、损伤严重程度和紧急干预方面具有更高的敏感性,而 SIPA 在这些结局方面的特异性较高。

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