Endocrinology Division, Department of Medical Specialities, MTI-Khyber Teaching Hospital, Peshawar, Pakistan.
Department of Diabetes, Endocrinology and Metabolic Diseases, MTI-Hayatabad Medical Complex, Peshawar, Pakistan.
Endocr Pract. 2024 Oct;30(10):951-956. doi: 10.1016/j.eprac.2024.06.013. Epub 2024 Jul 4.
The objectives of this study were to evaluate the stratification of people with diabetes mellitus (DM) based on the International Diabetes Federation-Diabetes and Ramadan 2021 risk calculator into different risk categories and assess their intentions to fast and outcomes of fasting during the holy month of Ramadan.
This was a 3-month prospective study that was performed from February 9, 2023, to May 6, 2023 (6 weeks before Ramadan until 6 weeks after Ramadan), at a tertiary care hospital in Pakistan. Data regarding glycemic control, characteristics and complications of diabetes, comorbidities, and the various factors that influence fasting were gathered from patients of either sex aged 18 to 80 years with any type of diabetes. The International Diabetes Federation-Diabetes and Ramadan 2021 risk calculation and recommendation were made accordingly for each patient.
This study comprised of 460 participants with DM, with 174 males (37.8%) and 286 females (62.2%). The risk categorization showed that 209 (45.4%), 107 (23.3%), and 144 (31.3%) of the participants were in the low-, moderate-, and high-risk categories, respectively. Of the 144 high-risk patients who fasted, 57.9% experienced hypoglycemia (P <.0001). The recommendation of fasting showed statistically significant differences with risk categories, intention to fast, hypoglycemia, type of DM, duration of DM, level of glycemic control, and days of fasting (P <.001).
A statistically significant number of participants in the high-risk group who fasted experienced complications. This reiterates the importance of rigorous adherence to the medical recommendations.
本研究旨在根据国际糖尿病联合会-糖尿病与斋月 2021 风险计算器，将糖尿病患者分层为不同风险类别，并评估他们在斋月期间斋戒的意愿和斋戒结果。
这是一项前瞻性研究，于 2023 年 2 月 9 日至 5 月 6 日（斋月前 6 周至斋月后 6 周）在巴基斯坦的一家三级保健医院进行。收集了年龄在 18 至 80 岁之间的任何类型糖尿病患者的血糖控制情况、糖尿病特征和并发症、合并症以及影响斋戒的各种因素的数据。根据每位患者的情况，进行了国际糖尿病联合会-糖尿病与斋月 2021 风险计算和推荐。
本研究共纳入 460 名糖尿病患者，其中男性 174 名（37.8%），女性 286 名（62.2%）。风险分类显示，209 名（45.4%）、107 名（23.3%）和 144 名（31.3%）患者分别处于低、中、高风险类别。在 144 名高风险患者中，有 57.9%（P<0.0001）出现了低血糖。斋戒的推荐与风险类别、斋戒意愿、低血糖、糖尿病类型、糖尿病病程、血糖控制水平和斋戒天数均存在统计学显著差异（P<0.001）。
在高风险组中，有相当数量的斋戒参与者出现了并发症。这再次强调了严格遵循医学建议的重要性。
