Department of Radiology, University of California Davis, Sacramento, CA, USA; Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Radiology, University of California Davis, Sacramento, CA, USA.
PET Clin. 2024 Oct;19(4):495-504. doi: 10.1016/j.cpet.2024.05.005. Epub 2024 Jul 4.
[F]fluoro-2-deoxy-d-glucose PET/computed tomography has been implemented in the management of patients with lymphoma, offering real-time metabolic information on lymphoma with the promise of more accurate staging, treatment response assessment, prognostication, and early detection of disease recurrence. The clinical management of lymphoproliferative disease has recently, rapidly evolved from initial chemotherapeutic to the use of immunotherapy, targeted agents, and to the use of chimeric antigen receptor T-cell therapies. The implementation of these new systems and imaging protocols together with new tracer development creates, in the field of lymphoproliferative disease, both opportunities and challenges that will be detailed in this comprehensive literature review.
氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描已应用于淋巴瘤患者的管理中,提供了实时的淋巴瘤代谢信息,有望实现更准确的分期、治疗反应评估、预后和疾病复发的早期检测。淋巴增生性疾病的临床管理最近已从最初的化疗迅速发展到免疫疗法、靶向药物以及嵌合抗原受体 T 细胞疗法的应用。这些新系统和成像方案的实施以及新型示踪剂的开发,在淋巴增生性疾病领域既带来了机遇,也带来了挑战,本文将对此进行全面的文献综述。