肾移植急性排斥反应组织学特征的回顾性研究及与循环T细胞群体的比较。
Retrospective study of histological features of acute rejection in renal allografts and comparison with circulating T cell populations.
作者信息
Wyatt J, Aparicio S R, Guillou P
出版信息
J Clin Pathol. 1985 Aug;38(8):858-63. doi: 10.1136/jcp.38.8.858.
Abstract
The histological severity of acute rejection in renal allografts was determined for 39 rejection episodes in 30 renal transplant recipients. Data were compared with the peripheral blood T cell subset ratios measured before and at the onset of the rejection episode. T cell subset ratios showed no correlation with the histological severity of rejection, nor with the reversibility of the rejection episode. The grade of histological rejection on biopsy was predictive of graft survival. We conclude that renal biopsy remains the best method for determining the severity and outcome of acute allograft rejection episodes.
摘要
对30例肾移植受者的39次排斥反应进行了肾移植急性排斥反应的组织学严重程度测定。将数据与排斥反应发作前和发作时测量的外周血T细胞亚群比例进行比较。T细胞亚群比例与排斥反应的组织学严重程度以及排斥反应发作的可逆性均无相关性。活检时的组织学排斥分级可预测移植物存活情况。我们得出结论，肾活检仍然是确定急性同种异体移植排斥反应发作的严重程度和结果的最佳方法。
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Retrospective study of histological features of acute rejection in renal allografts and comparison with circulating T cell populations.肾移植急性排斥反应组织学特征的回顾性研究及与循环T细胞群体的比较。
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本文引用的文献
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Interstitial mononuclear cell populations in renal graft rejection. Identification by monoclonal antibodies in tissue sections.肾移植排斥反应中的间质单核细胞群体。通过组织切片中的单克隆抗体进行鉴定。
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