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[自发性脑脊液耳漏的临床诊断与治疗分析]

[Clinical diagnosis and treatment analysis of spontaneous cerebrospinal fluid otorrhoea].

作者信息

Zhang Fan, Zhang Wenjing, Xuan Han, Zhang Ziyu, Li Sujuan, Meng Juan, Lu Xing, Qin Zhaobing

机构信息

Department of Otology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,450052,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Jul;38(7):584-588. doi: 10.13201/j.issn.2096-7993.2024.07.005.

Abstract

To investigate the clinical features, imaging findings, surgical methods, diagnostic and treatment experience of spontaneous cerebrospinal fluid otorrhoea. The clinical data of 11 patients with spontaneous cerebrospinal fluid otorrhoea treated surgically at our hospital from May 2018 to May 2023 were retrospectively analyzed. The medical data included medical history, imaging data, leak location, surgical repair method, treatment effect and postoperative follow-up. Among the 11 surgical patients, 4 patients were initially diagnosed with secretory otitis media, 1 was initially diagnosed with purulent otitis media, and 5 patients had a history of meningitis or presented because meningitis as the initial diagnosis. There were 2 cases of cerebrospinal fluid leakage repaired through the ear canal pathway and 9 cases of cerebrospinal fluid leakage repaired through the mastoid pathway. During the operation, leaks were located in the stapes floor plate in 4 cases, sinus meningeal angle in 1 case, posterior cranial fossa combined with middle cranial fossa in 1 case, middle cranial fossa in 4 cases, and labyrinthine segment of the internal auditory canal and facial nerve canal in 1 case. Ten patient was successfully repaired, and another patient developed intracranial hypertension after surgery, with symptoms alleviated by a lateral ventriculoperitoneal shunt. Postoperative follow-up ranged from 6 months to 4 years, and there was no CSF otorrhoea and meningitis recurrence. The incidence of spontaneous cerebrospinal fluid otorrhea is low, the clinical symptoms are atypical, and the rate of delayed diagnosis or missed diagnosis and misdiagnosis is high. Surgery is currently the preferred treatment for spontaneous cerebrospinal fluid otorrhoea, and satisfactory results are usually achieved; During diagnosis and treatment, it is crucial to be vigilant for intracranial hypertension to prevent serious complications and irreversible damage.

摘要

探讨自发性脑脊液耳漏的临床特点、影像学表现、手术方法、诊断及治疗经验。回顾性分析2018年5月至2023年5月在我院接受手术治疗的11例自发性脑脊液耳漏患者的临床资料。医学资料包括病史、影像学资料、漏口位置、手术修复方法、治疗效果及术后随访情况。11例手术患者中,4例初诊为分泌性中耳炎,1例初诊为化脓性中耳炎,5例有脑膜炎病史或因脑膜炎初诊就诊。经耳道途径修补脑脊液漏2例,经乳突途径修补脑脊液漏9例。术中发现漏口位于镫骨底板4例,脑膜窦角1例,后颅窝合并中颅窝1例,中颅窝4例,内耳道迷路段及面神经管1例。10例患者修补成功,1例术后出现颅内高压,经侧脑室-腹腔分流术后症状缓解。术后随访6个月至4年,无脑脊液耳漏及脑膜炎复发。自发性脑脊液耳漏发病率低,临床症状不典型,漏诊、误诊率高。手术是目前治疗自发性脑脊液耳漏的首选方法,通常可取得满意效果;诊治过程中需警惕颅内高压,预防严重并发症及不可逆损害。

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