Li Lin, Liu Yi, Wang Shaoqing
Department of Gynecology, Binzhou People's Hospital, Binzhou, China.
Department of Oncology, Binzhou People's Hospital, Binzhou, China.
Wideochir Inne Tech Maloinwazyjne. 2024 Jun;19(2):160-167. doi: 10.5114/wiitm.2024.138767. Epub 2024 Apr 10.
Uterine artery embolization (UAE) and hysterectomy are often used to treat uterine myoma. Nevertheless, the impact of these two treatments on postoperative ovarian function remains uncertain.
To compare the postoperative ovarian function in individuals with uterine myoma who had UAE against hysterectomy.
Searches were conducted in the Wanfang, Web of Science, and PubMed databases to find qualifying studies. The data were combined and analyzed.
Seven publications were included in this meta-analysis. Uterus and uterine myoma volume were dramatically decreased by UAE (p < 0.00001 for both). The combined preoperative levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were similar in both groups. Three months postoperatively, the combined FSH (p = 0.28) and LH (p = 0.64) levels were similar in both groups, while the combined E2 level was notably higher in the UAE group compared to the hysterectomy group (p < 0.00001). Six months postoperatively, the combined postoperative FSH and LH levels were considerably lower in the UAE group compared to the hysterectomy group (p = 0.002 for both). However, the combined E2 levels were similar between the two groups (p = 0.07). Also, 12 months after surgery, the combined postoperative FSH and LH levels were remarkably lower in the UAE group compared to the hysterectomy group (p = 0.02 and p < 0.00001, respectively). However, the combined E2 levels were similar in both groups (p = 0.15).
UAE may provide superior preservation of postoperative ovarian function compared to hysterectomy in individuals with uterine myoma.
子宫动脉栓塞术（UAE）和子宫切除术常用于治疗子宫肌瘤。然而，这两种治疗方法对术后卵巢功能的影响仍不确定。
比较接受UAE和子宫切除术的子宫肌瘤患者的术后卵巢功能。
在万方、科学网和PubMed数据库中进行检索，以查找符合条件的研究。对数据进行合并和分析。
本荟萃分析纳入了7篇文献。UAE使子宫和子宫肌瘤体积显著减小（两者p均<0.00001）。两组术前促卵泡生成素（FSH）、促黄体生成素（LH）和雌二醇（E2）的联合水平相似。术后3个月，两组FSH联合水平（p = 0.28）和LH联合水平（p = 0.64）相似，而UAE组E2联合水平显著高于子宫切除组（p < 0.00001）。术后6个月，UAE组术后FSH和LH联合水平显著低于子宫切除组（两者p = 0.002）。然而，两组E2联合水平相似（p = 0.07）。此外，术后12个月，UAE组术后FSH和LH联合水平显著低于子宫切除组（分别为p = 0.02和p < 0.00001）。然而，两组E2联合水平相似（p = 0.15）。
与子宫切除术相比，UAE可能能更好地保留子宫肌瘤患者的术后卵巢功能。
