Hovsepian David M, Ratts Valerie S, Rodriguez Michael, Huang Jessica S, Aubuchon Mira G, Pilgram Thomas K
Mallinckrodt Institute of Radiology, Washington University, 510 South Kingshighway Boulevard, St. Louis, MO 63110, USA.
J Vasc Interv Radiol. 2006 Jul;17(7):1111-5. doi: 10.1097/01.RVI.0000228338.11178.C8.
To prospectively compare uterine artery embolization (UAE) versus myomectomy and hysterectomy with regard to ovarian function as measured by postprocedure follicle-stimulating hormone (FSH) levels and symptoms.
Fifty-five patients were prospectively enrolled in the study: 33 patients who underwent UAE, seven who underwent myomectomy, and 15 who underwent hysterectomy. Patients had serum FSH and estradiol levels measured on the third day of the menstrual cycle before their procedure and at regular follow-up visits for as long as 6 months. At these intervals, patients were also surveyed regarding menopausal symptoms.
Although a mild transient increase in mean FSH level after UAE was noted at 3 months, there were no statistically significant differences among the three groups in mean FSH levels at 1 month, 3 months, or 6 months of follow-up. Menopausal symptoms arose in the UAE and hysterectomy groups, but there was no statistically significant difference or permanent effect in either group.
There is no significant difference in impact on ovarian function after UAE, hysterectomy, or myomectomy at follow-up for a maximum of 6 months.
通过术后促卵泡激素（FSH）水平及症状来前瞻性比较子宫动脉栓塞术（UAE）与子宫肌瘤切除术及子宫切除术对卵巢功能的影响。
前瞻性纳入55例患者：33例行UAE，7例行子宫肌瘤切除术，15例行子宫切除术。患者在手术前月经周期第3天及长达6个月的定期随访时测定血清FSH和雌二醇水平。在这些时间点，还对患者进行绝经症状调查。
虽然UAE术后3个月时平均FSH水平有轻度短暂升高，但随访1个月、3个月或6个月时，三组的平均FSH水平无统计学显著差异。UAE组和子宫切除组出现了绝经症状，但两组均无统计学显著差异或永久性影响。
在最长6个月的随访中，UAE、子宫切除术或子宫肌瘤切除术对卵巢功能的影响无显著差异。
Zotero 插件