Lançoni Samira Said, Albuquerque Jocilene Pedroso, Nakato Adriane Muller, Souza de Nieto Gislayne Castro E, Tkac Cláudio Marcelo, Sigwalt Marcos Fabiano, Nohama Percy, Souto Larissa Riskalla Talamini, Nassif Paulo Afonso Nunes
Graduate Program in Principles of Surgery, Faculdade Evangélica Mackenzie do Paraná, Curitiba, Paraná, Brasil.
Graduate Program on Health Technology, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
J Multidiscip Healthc. 2024 Jul 3;17:3091-3100. doi: 10.2147/JMDH.S458528. eCollection 2024.
To analyze leptin levels in placental tissue and premature infants undergoing phototherapy and to evaluate the potential for prescribing passive exercise after phototherapy in this population.
This analytical, longitudinal, prospective cohort study included 108 parturients and their respective premature infants. Variables examined included weight, gestational age, body mass index, sex, serum leptin levels in placental tissue, serum bilirubin levels, and reticulocyte count.
When comparing each group to a leptin threshold, statistically significant differences were observed at all evaluated time points for placental leptin levels (p < 0.001). Additionally, reticulocyte count decreased in relation to rebound time (p < 0.004). No correlations were found between leptin/bilirubin levels, leptin/reticulocytes, onset of nutrition, and BMI/leptin levels.
The findings regarding leptin levels suggest that prescribing passive exercises to premature infants undergoing phototherapy may be feasible because this intervention did not increase leptin levels.
分析接受光疗的胎盘组织和早产儿的瘦素水平，并评估对该人群在光疗后开具被动运动处方的可能性。
这项分析性、纵向、前瞻性队列研究纳入了108名产妇及其各自的早产儿。所检查的变量包括体重、胎龄、体重指数、性别、胎盘组织中的血清瘦素水平、血清胆红素水平和网织红细胞计数。
将每组与瘦素阈值进行比较时，在所有评估时间点的胎盘瘦素水平均观察到统计学上的显著差异（p < 0.001）。此外，网织红细胞计数与反弹时间呈负相关（p < 0.004）。未发现瘦素/胆红素水平、瘦素/网织红细胞、营养开始时间和体重指数/瘦素水平之间存在相关性。
关于瘦素水平的研究结果表明，对接受光疗的早产儿开具被动运动处方可能是可行的，因为这种干预不会增加瘦素水平。
