Felippu Alexandre Wady Debes, Fontes Erica Batista, Felippu André Wady Debes, Ellery Bruna Coelho, Oliveira Ana Carolina Silveira de, Guimarães André Vicente, Cascio Filippo, Felippu Alexandre
Instituto Felippu de Otorrinolaringologia, São Paulo, SP, Brazil.
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Int Arch Otorhinolaryngol. 2024 Jun 4;28(3):e432-e439. doi: 10.1055/s-0043-1777293. eCollection 2024 Jul.
Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascularized tumor that affects almost exclusively male adolescents. Surgery is the treatment of choice for JNA. The present study is a 42-year retrospective review of a series of JNA cases treated surgically without previous embolization. The present is a retrospective, descriptive study based on medical records of 96 patients with JNA who underwent microscopic or endoscopic excision without previous embolization from 1978 to 2020 in a single institution. The patients were categorized according to the Andrews et al. stage, and data were collected on age, gender, tumor staging, surgical approach, affected side, and outcome. All patients were male, with an average age of 17 years. The predominant tumor stage consisted of type II, with 52.1%. A total of 33.3% of the patients were submitted to the microscopic technique and 66.7%, to the endonasal technique. The rate of intraoperative blood transfusion was of 17.7%. The present study reinforces that resection of JNA in various stages is viable without previous artery embolization.
青少年鼻咽血管纤维瘤（JNA）是一种几乎仅影响男性青少年的良性血管化肿瘤。手术是JNA的首选治疗方法。本研究是对一系列未经术前栓塞而接受手术治疗的JNA病例进行的42年回顾性研究。本研究是一项基于1978年至2020年在单一机构中96例未经术前栓塞而接受显微镜或内镜切除的JNA患者病历的回顾性描述性研究。患者根据安德鲁斯等人的分期进行分类，并收集有关年龄、性别、肿瘤分期、手术方式、患侧和结果的数据。所有患者均为男性，平均年龄17岁。主要肿瘤分期为II型，占52.1%。共有33.3%的患者采用显微镜技术，66.7%的患者采用鼻内技术。术中输血率为17.7%。本研究强化了在未经术前动脉栓塞的情况下，各个阶段的JNA切除都是可行的这一观点。
