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一例罕见的外阴乳头状汗腺瘤

A Rare Case of Hidradenoma Papilliferum of the Vulva.

作者信息

Dubey Tripti

机构信息

Apollo Hospital, Navi Mumbai, India.

出版信息

J Obstet Gynaecol India. 2024 Jun;74(3):275-277. doi: 10.1007/s13224-023-01821-4. Epub 2023 Nov 30.

Abstract

Hidradenoma Papilliferum is an uncommon benign neoplasm typically presents in the anogenital region of 30 to 49 years old females. Rarely it can be seen over the head and over modified apocrine glands area such as breast, external ear canal and eyelids. In these cases, it is referred to as Ectopic Hidradenoma Papilliferum. It usually arises from mammary like glands or apocrine glands, in middle aged females. It has histopathological similarities to intraductul papilloma of breast. Clinically It presents as an isolated dermal or subcutaneous nodule which is said to have no connection to the epidermis. Interestingly the lack of communication with the overlying epithelium is accepted by some as criteria for diagnosis. It usually presents as a firm, flesh to red- coloured nodule in the anogenital area. The nodule is composed of tubules and papillary structures arranged in a frond like pattern. Here I present a case report of 33 Years old unmarried, sexually active female, presented with complaint of, a small swelling over perineum for last 8 months. The swelling has been growing very slowly without any other associated complaints. A biopsy was taken on an outpatient basis which confirmed the diagnosis and patient was treated with complete excision of the lesion.

摘要

乳头汗腺瘤是一种罕见的良性肿瘤,通常出现在30至49岁女性的肛门生殖器区域。很少能在头部以及乳腺、外耳道和眼睑等大汗腺区域见到。在这些情况下,它被称为异位乳头汗腺瘤。它通常起源于中年女性的乳腺样腺体或大汗腺。它在组织病理学上与乳腺导管内乳头状瘤相似。临床上它表现为一个孤立的真皮或皮下结节,据说与表皮没有联系。有趣的是,一些人将与上皮无连通性作为诊断标准。它通常表现为肛门生殖器区域一个坚实的、肉色至红色的结节。该结节由呈叶状排列的小管和乳头状结构组成。在此我报告一例33岁未婚、有性生活的女性病例,她因会阴处一个小肿物就诊,该肿物已持续8个月。肿物生长非常缓慢,无任何其他相关症状。门诊进行了活检,确诊后对患者进行了病变完整切除治疗。

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本文引用的文献

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Hidradenoma Papilliferum: Everyone Else's Diagnosis.乳头汗腺瘤:别人的诊断结果
Indian J Dermatol. 2020 Mar-Apr;65(2):151-153. doi: 10.4103/ijd.IJD_256_18.
2
Hidradenoma papilliferum of the vulva.外阴乳头状汗腺瘤
Indian Dermatol Online J. 2014 Oct;5(4):523-4. doi: 10.4103/2229-5178.142541.
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Hidradenoma papilliferum with a ductal carcinoma in situ component: case report and review of the literature.
Am J Dermatopathol. 2008 Aug;30(4):392-4. doi: 10.1097/DAD.0b013e31817c6a7d.
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Ectopic hidradenoma papilliferum: a case report and review of the literature.
J Am Acad Dermatol. 1999 Jul;41(1):115-8. doi: 10.1016/s0190-9622(99)70418-4.

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