Arjomand Abdullah, Myers Andrew, Akella Padmastuti
Division of Pulmonary, Critical Care and Sleep Medicine, University of South Florida, United States.
Respir Med Case Rep. 2024 Jun 8;51:102071. doi: 10.1016/j.rmcr.2024.102071. eCollection 2024.
An elderly woman with a history of myelodysplastic syndrome complicated by cavitary pneumonia treated with antibiotics and antifungal therapy was admitted with severe sepsis and pulmonary opacities on imaging. Pulmonary infection with , was diagnosed on bronchopulmonary lavage (BAL). This common environmental fungus is known to cause rare but severe infection in immunocompromised hosts. The patient was diagnosed with progression to acute myeloid leukemia during the hospitalization for which chemotherapy was initiated. Despite broadening antifungal therapy, the patient developed multi-organ system failure and died.
一名有骨髓增生异常综合征病史并并发空洞性肺炎且接受过抗生素和抗真菌治疗的老年女性，因严重脓毒症和影像学上的肺部混浊而入院。经支气管肺灌洗（BAL）诊断为肺部感染 。这种常见的环境真菌已知会在免疫功能低下的宿主中引起罕见但严重的感染。患者在住院期间被诊断为进展为急性髓系白血病，并因此开始化疗。尽管扩大了抗真菌治疗范围，但患者仍出现多器官系统衰竭并死亡。
