中性粒细胞/淋巴细胞比值在重度烧伤患者中的预后价值
PROGNOSTIC VALUES OF NEUTROPHIL/LYMPHOCYTE RATIO IN SEVERE BURN PATIENTS.
作者信息
Hung T D, Lam N N, Hung N T
机构信息
Le Huu Trac National Burn Hospital, Viet Nam.
Medical Military University, Viet Nam.
出版信息
Ann Burns Fire Disasters. 2024 Jun 30;37(2):124-129. eCollection 2024 Jun.
The aim of this study was to evaluate the characteristics and prognostic value of the neutrophil/lymphocyte ratio (NLR) in patients with severe burns. A retrospective study was conducted on 245 burn patients over 18 years old without comorbidity or combined injury, burn extent ≥20% TBSA, hospitalized within 24 hours after burn. The collected criteria included patient characteristics, NLR on admission, 3 and 7 day after burn, and outcome. The results showed that NLR was higher than the normal value at all collected times. In addition, compared to the survivor group, NLR on admission, 3 and 7 day after burn was significantly higher in the mortality group (p <.01). Multivariate analysis found that the NLR on the 7 day postburn was an independent factor associated with mortality (p <.05), along with the increase in age, burn extent, and presence of inhalation injury (AUC = .85; cut off: 14.13; sensitivity: 75% and specificity: 83.43%). In conclusion, NLR on the 7 day post burn may be used as a predictive factor for mortality amongst severe burn patients.
本研究旨在评估严重烧伤患者中性粒细胞/淋巴细胞比值（NLR）的特征及预后价值。对245例18岁以上、无合并症或复合伤、烧伤面积≥20%TBSA且在烧伤后24小时内入院的烧伤患者进行了一项回顾性研究。收集的标准包括患者特征、入院时、烧伤后3天和7天的NLR以及结局。结果显示，在所有收集时间点NLR均高于正常值。此外，与存活组相比，死亡组入院时、烧伤后3天和7天的NLR显著更高（p<.01）。多因素分析发现，烧伤后7天的NLR是与死亡率相关的独立因素（p<.05），同时还有年龄增加、烧伤面积和吸入性损伤（AUC=.85；截断值：14.13；敏感性：75%，特异性：83.43%）。总之，烧伤后7天的NLR可作为严重烧伤患者死亡率的预测因素。
Zotero 插件