Tidwell Jasmine, Thakkar Bianca, Wu George Y
Department of Medicine, University of Connecticut Health Center, Farmington, CT, USA.
Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT, USA.
J Clin Transl Hepatol. 2024 Jun 28;12(6):594-606. doi: 10.14218/JCTH.2024.00054. Epub 2024 May 20.
Splenic venous hypertension or left-sided portal hypertension is a rare condition caused by an obstruction of the splenic vein. Usually, it presents with upper gastrointestinal bleeding in the absence of liver disease. Etiologies can be classified based on the mechanism of development of splenic vein hypertension: compression, stenosis, inflammation, thrombosis, and surgically decreased splenic venous flow. Diagnosis is established by various imaging modalities and should be suspected in patients with gastric varices in the absence of esophageal varices, splenomegaly, or cirrhosis. The management and prognosis vary depending on the underlying etiology but generally involve reducing splenic venous pressure. The aim of this review was to summarize the etiologies of splenic venous hypertension according to the mechanism of development.
脾静脉高压或左侧门静脉高压是一种由脾静脉阻塞引起的罕见病症。通常，它在无肝脏疾病的情况下表现为上消化道出血。病因可根据脾静脉高压的发展机制进行分类：压迫、狭窄、炎症、血栓形成以及手术导致的脾静脉血流减少。通过各种成像方式可确立诊断，对于无食管静脉曲张、脾肿大或肝硬化但有胃静脉曲张的患者应怀疑此病。治疗和预后因潜在病因而异，但一般都涉及降低脾静脉压力。本综述的目的是根据发展机制总结脾静脉高压的病因。
