• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

实施透析期间肠外营养成功临床经验的路线图。

A roadmap for implementing a successful clinical experience with intradialytic parenteral nutrition.

机构信息

Department of Nephrology, FISABIO, Hospital Universitari Doctor Peset, Valencia, Spain; Department of Medicine, Universitat de València, Spain; Multidisciplinary Renal Nutrition Working Group, Spanish Society of Nephrology, Spain.

Department of Nephrology, FISABIO, Hospital Universitari Doctor Peset, Valencia, Spain.

出版信息

Clin Nutr ESPEN. 2024 Oct;63:322-331. doi: 10.1016/j.clnesp.2024.06.044. Epub 2024 Jul 1.

DOI:10.1016/j.clnesp.2024.06.044
PMID:38976478
Abstract

BACKGROUND AND AIMS

Intradialytic parenteral nutrition (IDPN) is a safe and effective patient-tailored nutritional strategy for providing nutrient supplementation to malnourished or at risk of malnutrition patients on hemodialysis (HD), who did not adequately respond to intensive dietary counselling and oral nutritional supplementation. Although IDPN is recommended by current ESPEN and KDOQI guidelines for nutrition in HD patients, none of these documents informs how to successfully implement this therapy, being the lack of knowledge on practical aspects of IDPN one of the main limitations to its use. The aim of this narrative review was to provide a practical roadmap for guiding the nephrologists, dietitians, and renal nurses in their everyday clinical practice about the use of IDPN.

METHODS

A multidisciplinary group formed by specialists from the areas of Nephrology and Nutrition agreed to address different practical aspects related to IDPN in HD patients. Based on the available evidence in the literature and on the authors' clinical experience, different topics were selected to develop a detailed plan for implementing a successful experience with IDPN, proposing a practical IDPN roadmap.

RESULTS

This IDPN roadmap provides practical information on when an IDPN should be started; what type of nutrients should be part of an IDPN; how the IDPN should be administered; how the effectiveness and safety of the IDPN should be monitored; how to determine the effectiveness of IDPN; and the conditions that advise discontinuing the IDPN.

CONCLUSIONS

IDPN is a safe and effective nutritional therapy for HD patients, although the lack of staff training may limit its use. This review addresses different practical aspects of IDPN, helping interdisciplinary teams in their daily clinical practice to improve the nutritional care of HD patients, either malnourished or at risk of malnutrition.

摘要

背景和目的

间歇性透析期间的肠外营养(IDPN)是一种安全有效的个体化营养策略,可用于为接受血液透析(HD)的营养不良或有营养不良风险的患者提供营养补充,这些患者对强化饮食咨询和口服营养补充没有充分反应。虽然 IDPN 被目前的 ESPEN 和 KDOQI 指南推荐用于 HD 患者的营养治疗,但这些文件都没有说明如何成功实施这种治疗方法,对 IDPN 实际方面的了解不足是其使用的主要限制之一。本叙述性综述的目的是为肾脏病医生、营养师和肾脏护士提供一个实用的路线图,指导他们在日常临床实践中使用 IDPN。

方法

一个由肾脏病学和营养学领域的专家组成的多学科小组同意解决与 HD 患者 IDPN 相关的不同实际方面。根据文献中的现有证据和作者的临床经验,选择了不同的主题,以制定一个详细的计划,以成功实施 IDPN 经验,提出一个实用的 IDPN 路线图。

结果

该 IDPN 路线图提供了有关何时应开始 IDPN、IDPN 应包含哪些类型的营养素、如何进行 IDPN 管理、如何监测 IDPN 的有效性和安全性、如何确定 IDPN 的有效性以及建议停止 IDPN 的条件等方面的实用信息。

结论

IDPN 是一种安全有效的 HD 患者营养治疗方法,尽管缺乏员工培训可能会限制其使用。本综述解决了 IDPN 的不同实际方面的问题,帮助跨学科团队在日常临床实践中改善 HD 患者的营养护理,无论是营养不良还是有营养不良风险的患者。

相似文献

1
A roadmap for implementing a successful clinical experience with intradialytic parenteral nutrition.实施透析期间肠外营养成功临床经验的路线图。
Clin Nutr ESPEN. 2024 Oct;63:322-331. doi: 10.1016/j.clnesp.2024.06.044. Epub 2024 Jul 1.
2
Intradialytic parenteral nutrition in maintenance hemodialysis patients suffering from protein-energy wasting. Results of a multicenter, open, prospective, randomized trial.维持性血液透析患者蛋白能量消耗的透析中肠外营养。一项多中心、开放、前瞻性、随机试验的结果。
Clin Nutr. 2017 Feb;36(1):107-117. doi: 10.1016/j.clnu.2015.11.016. Epub 2015 Dec 12.
3
Acute responses of gastrointestinal hormones to both oral and parenteral intradialytic nutrition.口服和肠外透析中胃肠激素的急性反应。
Am J Nephrol. 2010;32(3):272-278. doi: 10.1159/000319200. Epub 2010 Aug 12.
4
Intradialytic parenteral nutrition in end-stage renal disease: practical aspects, indications and limits.终末期肾病的透析期间胃肠外营养:实际情况、适应证及局限性
J Nephrol. 2014 Aug;27(4):377-83. doi: 10.1007/s40620-014-0051-6. Epub 2014 Feb 21.
5
The beneficial effects of intradialytic parenteral nutrition in hemodialysis patients with protein energy wasting: a prospective randomized controlled trial.透析期间肠外营养对蛋白质能量消耗的血液透析患者的有益作用:一项前瞻性随机对照试验。
Sci Rep. 2022 Mar 16;12(1):4529. doi: 10.1038/s41598-022-08726-8.
6
Systematic review of evidence for the use of intradialytic parenteral nutrition in malnourished hemodialysis patients.系统评价血液透析患者营养不良时使用透析中肠外营养的证据。
J Ren Nutr. 2010 Jan;20(1):1-7. doi: 10.1053/j.jrn.2009.08.003. Epub 2009 Sep 27.
7
Use of Intradialytic Parenteral Nutrition in Patients Undergoing Hemodialysis.血液透析患者的透析中肠外营养应用。
Nutr Clin Pract. 2018 Dec;33(6):767-771. doi: 10.1002/ncp.10190. Epub 2018 Sep 12.
8
Intradialytic oral nutrition improves protein homeostasis in chronic hemodialysis patients with deranged nutritional status.透析期间口服营养改善营养状况紊乱的慢性血液透析患者的蛋白质稳态。
J Am Soc Nephrol. 2006 Nov;17(11):3149-57. doi: 10.1681/ASN.2006040413. Epub 2006 Oct 4.
9
Malnutrition in patients undergoing hemodialysis: is intradialytic parenteral nutrition the answer?接受血液透析患者的营养不良:透析期间胃肠外营养是解决办法吗?
Pharmacotherapy. 2004 Dec;24(12):1748-58. doi: 10.1592/phco.24.17.1748.52337.
10
Revisiting Intradialytic Parenteral Nutrition: How Can We Apply the Evidence in Clinical Practice?重新审视透析期间肠外营养:我们如何在临床实践中应用这些证据?
Adv Kidney Dis Health. 2023 Nov;30(6):502-507. doi: 10.1053/j.akdh.2023.07.006.

引用本文的文献

1
Nutritional outcomes between different techniques of intradialytic amino acid replacement: a randomized controlled trial.不同血液透析期间氨基酸补充技术的营养结局:一项随机对照试验。
Clin Kidney J. 2024 Nov 18;18(1):sfae361. doi: 10.1093/ckj/sfae361. eCollection 2025 Jan.