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机器人辅助与传统全髋关节置换术后阿片类药物使用:国家数据库分析。

Opioid Use After Robotic-Assisted Versus Conventional Total Hip Arthroplasty: A National Database Analysis.

出版信息

Orthopedics. 2024 Sep-Oct;47(5):289-294. doi: 10.3928/01477447-20240702-03. Epub 2024 Jul 8.

DOI:10.3928/01477447-20240702-03
PMID:38976847
Abstract

BACKGROUND

In this study, we tested the null hypothesis that robotic-assisted total hip arthroplasty (THA) vs conventional THA was not associated with (1) the amount of postoperative opioid use and (2) the incidence of new, persistent opioid use.

MATERIALS AND METHODS

We used a large, national administrative database to identify patients 50 years and older undergoing primary robotic or conventional THA. Patients with hip fractures or a history of malignancy, hip infection, or opioid use disorder were excluded. Patients who filled an opioid prescription within 1 year to 30 days preoperatively or who underwent a subsequent procedure within 1 year after THA were excluded. Outcomes included the morphine milligram equivalents (MMEs) filled within the THA perioperative period and the incidence of new, persistent opioid use. Multivariable logistic regression models were used to evaluate associations between robotic-assisted THA and new, persistent opioid use, adjusting for age, sex, insurance plan, region, location of surgery, and comorbidities.

RESULTS

In the postoperative period, robotic-assisted THA, compared with conventional THA, was associated with a lower mean total MMEs filled per patient (452.2 vs 517.1; <.001) and a lower mean MMEs per patient per day (71.53 vs 74.64; <.001). Patients undergoing robotic-assisted THA had decreased odds of developing new, persistent opioid use compared with patients undergoing conventional THA (adjusted odds ratio, 0.82 [95% CI, 0.74-0.90]).

CONCLUSION

Robotic-assisted THA is associated with lower postoperative opioid use and a decreased odds of developing new, persistent opioid use compared with conventional THA. For the purposes of reducing opioid use, our results support the adoption of robotic-assisted THA. [. 2024;47(5):289-294.].

摘要

背景

本研究旨在检验以下假设,即与传统全髋关节置换术(THA)相比,机器人辅助全髋关节置换术(THA)与(1)术后阿片类药物使用量和(2)新发持续性阿片类药物使用无关。

材料和方法

我们使用大型国家行政数据库,确定了 50 岁及以上行初次机器人辅助或传统 THA 的患者。排除髋部骨折或恶性肿瘤、髋关节感染或阿片类药物使用障碍病史的患者。排除在术前 1 年内至 30 天内开具阿片类药物处方或在 THA 后 1 年内进行后续手术的患者。评估指标包括 THA 围手术期内阿片类药物使用的吗啡毫克当量(MME)和新发持续性阿片类药物使用的发生率。多变量逻辑回归模型用于评估机器人辅助 THA 与新发持续性阿片类药物使用之间的相关性,调整年龄、性别、保险计划、地区、手术地点和合并症。

结果

在术后期间,与传统 THA 相比,机器人辅助 THA 导致每位患者的平均总 MME 用量减少(452.2 比 517.1;<.001),每位患者的平均 MME 日用量减少(71.53 比 74.64;<.001)。与接受传统 THA 的患者相比,接受机器人辅助 THA 的患者新发持续性阿片类药物使用的可能性降低(校正优势比,0.82[95%CI,0.74-0.90])。

结论

与传统 THA 相比,机器人辅助 THA 与术后阿片类药物使用减少和新发持续性阿片类药物使用的可能性降低相关。为了减少阿片类药物的使用,我们的结果支持采用机器人辅助 THA。[2024;47(5):289-294.]。

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Opioid Use After Robotic-Assisted Versus Conventional Total Hip Arthroplasty: A National Database Analysis.机器人辅助与传统全髋关节置换术后阿片类药物使用:国家数据库分析。
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