Medical College of Wisconsin, Milwaukee, USA.
Tufts Medical Center, Tufts University School of Medicine, Boston, USA.
J Med Case Rep. 2024 Jul 9;18(1):327. doi: 10.1186/s13256-024-04485-4.
Red Ear Syndrome is a burning sensation and erythema of the ear, associated with a various number of disorders including migraine, trigeminal neuralgia, autoimmune disorders etc. Theories for RES pathophysiology have developed from current understandings of comorbid conditions. Characterizing the underlying mechanism of RES is crucial for defining effective treatments.
Three caucasian patients, ages 15, 47, and 67 years, with migraine, one with erythromelalgia are reported in this manuscript. RES pathophysiology is not fully understood due to its variable clinical presentation and numerous comorbid conditions, making it difficult to identify effective treatments.
RES seems to be largely treatment-resistant, and most options involve treating the associated disorders and minimizing pain. Further investigation of future cases should lead to a more comprehensive understanding of the fundamental cause of RES and, hopefully, successful treatments.
红耳综合征是一种耳部灼热感和红斑，与包括偏头痛、三叉神经痛、自身免疫性疾病等多种疾病有关。RES 病理生理学的理论是从目前对伴发疾病的理解中发展而来的。表征 RES 的潜在机制对于确定有效的治疗方法至关重要。
本文报告了 3 名白人患者，年龄分别为 15 岁、47 岁和 67 岁，患有偏头痛，其中 1 名患有红斑性肢痛症。由于其临床表现多样且伴发疾病众多，RES 病理生理学尚未完全阐明，因此难以确定有效的治疗方法。
RES 似乎对大多数治疗方法都有抗性，并且大多数选择都涉及治疗相关疾病和减轻疼痛。对未来病例的进一步研究应能更全面地了解 RES 的根本原因，并有望实现成功的治疗。
