Materials Science and Technology Division, CSIR-National Institute of Interdisciplinary Science and Technology, Industrial Estate, Thiruvananthapuram-695 019, Kerala, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad- 201002, India.
J Mater Chem B. 2024 Aug 7;12(31):7557-7563. doi: 10.1039/d4tb01133c.
In this work, we demonstrate the electrochemical (EC) sensing of glycine (GLY) on a gold-copper nanocluster on nitrogen-doped graphene quantum dot-modified (indigenously fabricated) screen-printed electrode (AuCuNC@N-GQD/SPE). SPE was fabricated by step-by-step printing of reference, working, and counter electrodes to develop an all-printed SPE. A comparison strategy between SPE and the glassy carbon electrode (GCE) towards the EC sensing of GLY was carried out. The sensing performance was enhanced while replacing GCE with SPE. The limit of detection (LOD) for GLY obtained by EC sensing with AuCuNC@N-GQD/GCE was 10 nM and that with AuCuNC@N-GQD/SPE was 10 times lower, 1 nM, and is the lowest LOD value reported hitherto. Compared with AuCuNC@N-GQD/GCE, the current response of AuCuNC@N-GQD/SPE exhibited a ∼2.6-times enhancement with a sensitivity of 0.206 μA μM cm. Thus, the successful shift from GCE to SPE not only miniaturizes the sensor device but also enhances the electrochemical detection performance.
在这项工作中，我们展示了在氮掺杂石墨烯量子点修饰的（本地制备）丝网印刷电极（AuCuNC@N-GQD/SPE）上的金-铜纳米团簇对甘氨酸（GLY）的电化学（EC）传感。通过逐步打印参比电极、工作电极和对电极来制备全印刷 SPE。对 SPE 和玻碳电极（GCE）在 GLY 的 EC 传感方面进行了比较策略。用 SPE 代替 GCE 后，传感性能得到了提高。通过 AuCuNC@N-GQD/GCE 的 EC 传感获得的 GLY 的检测限（LOD）为 10 nM，而 AuCuNC@N-GQD/SPE 的 LOD 降低了 10 倍，为 1 nM，是迄今为止报道的最低 LOD 值。与 AuCuNC@N-GQD/GCE 相比，AuCuNC@N-GQD/SPE 的电流响应增强了约 2.6 倍，灵敏度为 0.206 μA μM cm。因此，从 GCE 到 SPE 的成功转变不仅使传感器设备小型化，而且还提高了电化学检测性能。
