School of Biology & Engineering (School of Health Medicine Modern Industry), Guizhou Medical University, No. 6 Ankang Road, Guian New District, Guiyang, 561113, China.
Hospital Infection and Preventive Health Care, Bijie Hospital of Zhejiang Provincial People's Hospital, Bijie, 551700, China.
Sci Rep. 2024 Jul 9;14(1):15854. doi: 10.1038/s41598-024-66639-0.
This study aimed to assess the current status and changing trends of the disease burden of stroke and its subtypes due to low dietary fiber intake in China from 1990 to 2019. In cases of stroke and its subtypes attributable to low dietary fiber, deaths, disability-adjusted life-years (DALYs), age-standardized mortality rates (ASMR), age-standardized DALYs rates (ASDR), and percentage change were used to assess disease burden. Data were obtained from the 2019 global burden of disease study. Trends were assessed using Joinpoint regression and age-period-cohort analysis. Between 1990 and 2019, there was a declining trend in stroke and its subtypes, ASDR and ASMR, as well as the corresponding number of deaths and DALYs, due to low dietary fiber intake in China. Subarachnoid hemorrhage (SH) showed the greatest decrease, followed by intracerebral hemorrhage (IH) and ischemic stroke (IS). Local drift curves showed a U-shaped distribution of stroke, IS, and IH DALYs across the whole group and sex-based groups. For mortality, the overall and male trends were similar to those for DALYs, whereas female stroke, IH, and IS showed an upward trend. The DALYs for stroke and IH showed a clear bimodal distribution, IS showed an increasing risk with age. For mortality, the SH subtype showed a decreasing trend, whereas other subtypes showed an increasing risk with age. Both the period and cohort rates of stroke DALYs and motality due to low dietary fiber have declined. Males had a higher risk of DALYs and mortality associated with low fiber levels. The burden of stroke and its subtypes associated with a low-fiber diet in China has been declining over the past 30 years, with different patterns of change for different stroke subtypes and a higher burden for males, highlighting the differential impact of fiber intake on stroke and its subtypes.
本研究旨在评估 1990 年至 2019 年中国因膳食纤维摄入量低导致的中风和其亚型的疾病负担现状和变化趋势。在归因于低膳食纤维的中风和其亚型病例中,使用死亡、伤残调整生命年(DALYs)、年龄标化死亡率(ASMR)、年龄标化 DALYs 率(ASDR)和百分比变化来评估疾病负担。数据来自 2019 年全球疾病负担研究。使用 Joinpoint 回归和年龄-时期-队列分析来评估趋势。1990 年至 2019 年,中国因膳食纤维摄入量低导致的中风和其亚型、ASDR 和 ASMR 以及相应的死亡和 DALYs 数量呈下降趋势。蛛网膜下腔出血(SH)降幅最大,其次是脑内出血(IH)和缺血性中风(IS)。总体和基于性别的本地漂移曲线显示中风、IS 和 IH 的 DALYs 呈 U 型分布。对于死亡率,整体和男性趋势与 DALYs 相似,而女性中风、IH 和 IS 呈上升趋势。中风和 IH 的 DALYs 呈明显双峰分布,IS 则随年龄增长呈上升风险。对于死亡率,SH 亚型呈下降趋势,而其他亚型则随年龄增长呈上升风险。低纤维饮食导致的中风 DALYs 和死亡率的时期和队列率均有所下降。男性的 DALYs 和死亡率与低纤维水平相关的风险更高。过去 30 年来,中国因低纤维饮食导致的中风和其亚型的负担一直在下降,不同中风亚型的变化模式不同,男性的负担更高,这突出表明纤维摄入量对中风和其亚型的影响存在差异。