Department of Psychology, Bournemouth University, Poole House, Talbot Campus, Fern Barrow, Poole, Dorset, BH12 5BB, UK.
Sci Rep. 2024 Jul 9;14(1):15846. doi: 10.1038/s41598-024-66158-y.
Recognition memory research has identified several electrophysiological indicators of successful memory retrieval, known as old-new effects. These effects have been observed in different sensory domains using various stimulus types, but little attention has been given to their similarity or distinctiveness and the underlying processes they may share. Here, a data-driven approach was taken to investigate the temporal evolution of shared information content between different memory conditions using openly available EEG data from healthy human participants of both sexes, taken from six experiments. A test dataset involving personally highly familiar and unfamiliar faces was used. The results show that neural signals of recognition memory for face stimuli were highly generalized starting from around 200 ms following stimulus onset. When training was performed on non-face datasets, an early (around 200-300 ms) to late (post-400 ms) differentiation was observed over most regions of interest. Successful cross-classification for non-face stimuli (music and object/scene associations) was most pronounced in late period. Additionally, a striking dissociation was observed between familiar and remembered objects, with shared signals present only in the late window for correctly remembered objects, while cross-classification for familiar objects was successful in the early period as well. These findings suggest that late neural signals of memory retrieval generalize across sensory modalities and stimulus types, and the dissociation between familiar and remembered objects may provide insight into the underlying processes.
再认记忆研究已经确定了几种成功记忆检索的电生理指标,称为新旧效应。这些效应在不同的感觉域中使用不同的刺激类型观察到,但很少关注它们的相似性或独特性以及它们可能共享的潜在过程。在这里,采用了一种数据驱动的方法来研究使用来自不同性别健康人类参与者的公开可用 EEG 数据,从六个实验中研究不同记忆条件之间共享信息内容的时间演变。使用涉及个人高度熟悉和不熟悉的面孔的测试数据集。结果表明,从刺激开始后大约 200 毫秒开始,面孔刺激的识别记忆的神经信号高度概括。当在非面孔数据集上进行训练时,在大多数感兴趣区域观察到早期(约 200-300 毫秒)到晚期(400 毫秒后)的分化。对于非面孔刺激(音乐和物体/场景关联)的成功跨类分类在晚期最为明显。此外,在熟悉的和被记住的物体之间观察到了惊人的分离,只有在正确记住的物体的晚期窗口中才存在共享信号,而对于熟悉的物体的跨类分类在早期也成功了。这些发现表明,记忆检索的晚期神经信号在感觉模态和刺激类型之间具有通用性,并且熟悉的和被记住的物体之间的分离可能提供对潜在过程的深入了解。