Ospedale Morgagni-Pierantoni, Forlì, Italy.
Ospedale degli Infermi, Faenza, Italy.
Eye (Lond). 2024 Nov;38(16):3065-3071. doi: 10.1038/s41433-024-03219-6. Epub 2024 Jul 9.
To investigate the outcomes of aqueous shunt exposure repair and to identify risk factors for recurrent exposure after surgical repair.
This is a retrospective interventional case series of consecutive patients who underwent repair of an exposed aqueous shunt. Demographic and clinical data were extracted from the patients' records and survival analysis was employed to determine the probability of survival of the repair without further exposure. Cox proportional regression analysis was utilised to identify potential risk factors for failure of the repair surgery.
Seventy-six eyes of 76 patients were included in the study. The probability of survival without further exposure was 76.2% (CI 66.9-86.8%), 72.7% (CI 62.8-84.1%) and 54.7% (40.5-73.7%) at 1,2 and 4 years, respectively. No eye in which the tube was repositioned in the anterior chamber or in the sulcus (n = 9; 11.8%) developed a recurrence of the exposure. A shorter interval from the time of tube insertion to the repair surgery (HR 2.87 [CI 1.11-7.39]; p = 0.03; reference longer interval), a history of previous surgical revision (HR 3.06 [1.15-8.12]; p = 0.02; reference no prior revision) and the use of a human pericardial donor patch at the time of revision (HR 3.43 [1.16-10.13]; p = 0.03; reference other than pericardium) was associated with an increased risk of exposure recurrence.
Aqueous shunt exposure revision is associated with reasonable mid and long term success. A shorter interval from tube insertion to exposure revision, previous revisions and the use of a human pericardium patch were associated with increased risk of failure.
探讨房水引流管暴露修复的结果,并确定手术修复后再次暴露的风险因素。
这是一项回顾性连续病例系列研究,纳入了接受暴露房水引流管修复的患者。从患者记录中提取人口统计学和临床数据,并进行生存分析,以确定无进一步暴露的修复成功率。采用 Cox 比例风险回归分析确定修复手术失败的潜在风险因素。
研究纳入了 76 例 76 只眼。无进一步暴露的生存概率分别为 76.2%(95%CI:66.9-86.8%)、72.7%(95%CI:62.8-84.1%)和 54.7%(95%CI:40.5-73.7%),随访时间分别为 1、2 和 4 年。在前房或结膜下重新定位引流管的 9 只眼(11.8%)未发生暴露复发。修复手术距引流管插入时间较短(HR 2.87,95%CI:1.11-7.39;p=0.03;参考间隔时间较长)、有既往手术翻修史(HR 3.06,95%CI:1.15-8.12;p=0.02;参考无既往翻修)和在翻修时使用人类心包供体补片(HR 3.43,95%CI:1.16-10.13;p=0.03;参考非心包)与暴露复发风险增加相关。
房水引流管暴露修复具有较好的中期和长期成功率。修复手术距引流管插入时间较短、有既往翻修史和使用人类心包补片与失败风险增加相关。