Department of Physiotherapy, Wrocław University of Health and Sport Sciences, Wrocław, Poland.
Med Sci Monit. 2024 Jul 10;30:e944406. doi: 10.12659/MSM.944406.
BACKGROUND The effects of cigarette smoking on the health of active smokers and passive smokers have long been known, in contrast to the effects of alternative forms of nicotine intake that are gaining popularity. The aim of the study was to assess the effects of smoking traditional cigarettes and alternative forms of nicotine intake on the functional state of the respiratory system of smokers and non-smokers. MATERIAL AND METHODS Study participants (n=60) were divided into 3 groups: non-smokers (control group), cigarette smokers, and nicotine alternative users. Respiratory function testing (spirometry), forced oscillation technique, and measurement of respiratory muscle strength (PImax, PEmax) were performed. All of the above respiratory function tests were performed in accordance with European Respiratory Society and American Thoracic Society recommendations. RESULTS Smokers and those using alternative forms of nicotine intake had significantly higher values, including resistance at 5 Hz% and 11 Hz%, among others. CONCLUSIONS Smokers and users of alternative forms of nicotine are characterized by reduced flow through the small bronchioles, as evidenced by a reduction in maximal expiratory flow at 25% of vital capacity. Smokers and users of alternative forms of nicotine have higher resistance values at the height of small and medium bronchioles. Assessment method of technical forced oscillation parameters is simple to perform to detect early airway changes and is an important element in the early diagnosis of changes in smokers. The correlation analysis showed a significant correlation between age of smoking initiation/use of alternative forms of nicotine and changes in mid bronchial resistance.
吸烟对主动吸烟者和被动吸烟者健康的影响早已为人所知,而与之相反的是,替代形式的尼古丁摄入的影响却越来越受到关注。本研究的目的是评估传统香烟吸烟和替代形式的尼古丁摄入对吸烟者和非吸烟者呼吸系统功能状态的影响。
研究参与者(n=60)分为 3 组:非吸烟者(对照组)、香烟吸烟者和尼古丁替代物使用者。进行了呼吸功能测试(肺活量测定法)、强迫振荡技术和呼吸肌强度测量(PImax、PEmax)。所有上述呼吸功能测试均按照欧洲呼吸学会和美国胸科学会的建议进行。
吸烟者和尼古丁替代物使用者的阻力值(包括 5 Hz%和 11 Hz%等)等显著更高。
吸烟者和尼古丁替代物使用者的小支气管通过气流减少,表现在肺活量的 25%处最大呼气流量减少。小气道和中等气道的阻力值在吸烟者和尼古丁替代物使用者中更高。技术强迫振荡参数的评估方法简单易行,可以检测早期气道变化,是早期诊断吸烟者气道变化的重要因素。相关性分析显示,吸烟开始年龄/使用尼古丁替代物与中支气管阻力变化之间存在显著相关性。