Author Affiliations : Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark (Drs Bjerre, Mols, Frausing, Eiskjær, Løgstrup, Kronborg, and Nielsen); Department of Clinical Medicine, Aarhus University, Aarhus, Denmark (Drs Bjerre, Mols, Frausing, Witt, Eiskjær, Løgstrup, Kronborg, and Nielsen); and Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark (Mr Bakos and Ms Horváth-Puhó).
J Cardiopulm Rehabil Prev. 2024 Sep 1;44(5):345-352. doi: 10.1097/HCR.0000000000000884. Epub 2024 Sep 3.
Labor market participation is an important rehabilitation goal for working-age patients living with heart failure (HF). Cardiac resynchronization therapy (CRT) reduces mortality and HF hospitalizations and improves quality of life, but no studies have investigated labor market participation following CRT. We therefore aimed to describe labor market participation in patients with HF before and after CRT implantation.
This region-wide register-based cohort study comprised patients with HF aged 40 to 63 yr, with ejection fraction ≤35% and QRS duration >130 milliseconds, who received a CRT system from 2000 to 2017 in the Central Denmark Region. Using unambiguous, individual-level linkage in Danish medical and administrative registries, we assessed weekly employment status from 1 yr prior to CRT implantation until 2 to 5 yr of follow-up and conducted stratified analyses by sociodemographic and disease-related risk factors.
We identified 546 patients, of whom 42% were in early retirement 1 yr prior to implantation. Active employment decreased from 45% to 19% from 1 yr before until implantation, declining primarily in the last 8 wk before implantation. The proportion of patients in active employment increased in the first 8 wk after CRT implantation and then stabilized, reaching 31% at 1-yr follow-up. We observed lower labor market participation in patients with older age, multimorbidity, lower educational level, and upgrade procedures, but higher in later calendar year.
In working-age patients with HF, labor market participation increased after CRT implantation, despite many patients being retired prior to implantation. We observed differences in active employment related to several sociodemographic and disease-related factors.
劳动力市场参与是心衰(HF)青壮年患者的重要康复目标。心脏再同步治疗(CRT)降低了死亡率和 HF 住院率,并改善了生活质量,但尚无研究调查 CRT 后的劳动力市场参与情况。因此,我们旨在描述 CRT 植入前后 HF 患者的劳动力市场参与情况。
本区域范围内基于登记的队列研究纳入了 2000 年至 2017 年期间在丹麦中央大区接受 CRT 系统治疗的年龄在 40 至 63 岁之间、射血分数≤35%且 QRS 持续时间>130 毫秒的 HF 患者。我们使用丹麦医疗和行政登记册中明确、个体层面的链接,评估了 CRT 植入前 1 年至随访 2 至 5 年期间的每周就业状况,并按社会人口统计学和疾病相关危险因素进行分层分析。
我们确定了 546 名患者,其中 42%在植入前 1 年提前退休。从植入前 1 年到植入前,活跃就业比例从 45%下降到 19%,主要下降发生在植入前的最后 8 周内。在 CRT 植入后的前 8 周内,患者活跃就业的比例增加,然后稳定下来,在 1 年随访时达到 31%。我们观察到年龄较大、合并症较多、教育程度较低以及升级程序的患者劳动力市场参与度较低,但在较晚的年份则较高。
在 HF 青壮年患者中,尽管许多患者在植入前已经退休,但 CRT 植入后劳动力市场参与度增加。我们观察到与一些社会人口统计学和疾病相关因素有关的活跃就业差异。