[从患有大肠杆菌败血症的家禽中分离出的大肠杆菌菌株对药物的敏感性]

[Sensitivity to drugs of Escherichia coli strains isolated from poultry with coli septicemia].

作者信息

Giurov B

出版信息

Vet Med Nauki. 1985;22(5):16-24.

Abstract

Investigations were carried out into the susceptibility of a total of 223 strains of Escherichia coli to therapeutic agents with the employment of the disk diffusion method. The organisms were isolated from internal organs and bone marrow of birds died of coli septicaemia. The serologic classification of the strains was defined with the use of 88 anti-group OK-agglutinating sera obtained through hyperimmunization of rabbits with the following Escherichia coli serotypes: 01-063, 068, 071, 073, 075, 078, 086, 0101, 0103, 0111-0114, 0119, 0124, 0129, 0135-0141, 0146, 0147, and 0149. It was found that serologically the strains referred as follows: 01-41 strains, 02-70 strains, 04-2 strains, 08-3 strains, 026-1 strain, 078-70 strains, 0111-2 strains, 0103-1 strain, 0141-1 strain. The number of untypable strains amounted to 32. Highest number of strains proved sensitive to colistin--96.06%, the remaining drugs following in a descending order: flumequine--95.65%, apramycin - 95.5%, gentamycin--93.72%, amoxicillin--93,8%, amikacin--88.57%, carbenicillin--86.88%, furazolidone--83,13%, and kanamycin--79.36%. High was the percent of strains resistant to tetracycline--66.17%, spectinomycin--61.67%, ampicillin--51.12%, chloramphenicol--50.23%, and streptomycin--44.84%.

摘要

采用纸片扩散法对总共223株大肠杆菌对治疗药物的敏感性进行了研究。这些菌株是从死于大肠杆菌败血症的鸟类的内脏器官和骨髓中分离出来的。通过用以下大肠杆菌血清型对兔子进行超免疫获得的88种抗群OK凝集血清对菌株进行血清学分类：01 - 063、068、071、073、075、078、086、0101、0103、0111 - 0114、0119、0124、0129、0135 - 0141、0146、0147和0149。结果发现，这些菌株的血清学分类如下：01 - 41株、02 - 70株、04 - 2株、08 - 3株、026 - 1株、078 - 70株、0111 - 2株、0103 - 1株、0141 - 1株。无法分型的菌株数量为32株。对黏菌素敏感的菌株数量最多——96.06%，其余药物按敏感性从高到低依次为：氟甲喹——95.65%、阿普拉霉素——95.5%、庆大霉素——93.72%、阿莫西林——93.8%、阿米卡星——88.57%、羧苄青霉素——86.88%、呋喃唑酮——83.13%、卡那霉素——79.36%。对四环素耐药的菌株比例较高——66.17%，对壮观霉素耐药的比例为61.67%，对氨苄西林耐药的比例为51.12%，对氯霉素耐药的比例为50.23%，对链霉素耐药的比例为44.84%。