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"多学科快速通道"护理可显著降低至少 80 岁髋部骨折患者的死亡率:一项单中心回顾性研究。

"Multidisciplinary fast-track" care can significantly reduce risk of mortality among hip fracture patients at least 80 years old: a single-center retrospective study.

机构信息

Department of Anesthesiology, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou, Zhejiang, China.

Department of Anesthesiology & Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Affiliated Central Hospital Huzhou University, Huzhou, Zhejiang, China.

出版信息

BMC Geriatr. 2024 Jul 10;24(1):592. doi: 10.1186/s12877-024-05183-y.

Abstract

BACKGROUND

"Multidisciplinary fast-track" (MFT) care can accelerate recovery and improve prognosis after surgery, but whether it is effective in older people after hip fracture surgery is unclear.

METHODS

We retrospectively compared one-year all-cause mortality between hip fracture patients at least 80 years old at our institution who underwent hip fracture surgery between January 2014 and December 2018 and who then received MFT or conventional care. Multivariable regression was used to assess the association between MFT care and mortality after adjustment for confounders.

RESULTS

The final analysis included 247 patients who received MFT care and 438 who received conventional orthopedic care. The MFT group showed significantly lower one-year mortality (8.9% vs. 14.4%, P = 0.037). Log-rank testing of Kaplan-Meier survival curves confirmed the survival advantage. However, the two groups did not differ significantly in rates of mortality during hospitalization or at 30 or 90 days after surgery. Regression analysis confirmed that MFT care was associated with lower risk of one-year mortality (hazard ratio [HR] 0.47, 95% confidence interval [CI] 0.281-0.788, P = 0.04), and the survival benefit was confirmed in subgroups of patients with anemia (HR 0.453, 95% CI 0.268-0.767, P = 0.003) and patients with American Society of Anesthesiologists grade III (HR 0.202, 95% CI 0.08-0.51, P = 0.001).

CONCLUSIONS

MFT care can reduce one-year mortality among hip fracture patients at least 80 years old. This finding should be verified and extended in multi-center randomized controlled trials.

摘要

背景

“多学科快速通道”(MFT)护理可以加速手术后的康复并改善预后,但在老年髋部骨折患者中的效果尚不清楚。

方法

我们回顾性比较了我院 2014 年 1 月至 2018 年 12 月间接受髋部骨折手术的 80 岁以上髋部骨折患者,他们接受 MFT 或常规护理后的一年全因死亡率。多变量回归用于评估 MFT 护理与死亡率之间的关联,调整混杂因素后进行分析。

结果

最终分析纳入了 247 例接受 MFT 护理的患者和 438 例接受常规骨科护理的患者。MFT 组的一年死亡率明显较低(8.9% vs. 14.4%,P=0.037)。Kaplan-Meier 生存曲线的对数秩检验证实了生存优势。然而,两组患者在住院期间或术后 30 天或 90 天的死亡率没有显著差异。回归分析证实 MFT 护理与一年死亡率降低相关(风险比[HR]0.47,95%置信区间[CI]0.281-0.788,P=0.04),并且在贫血患者亚组(HR 0.453,95%CI 0.268-0.767,P=0.003)和美国麻醉医师协会(ASA)分级 III 患者亚组(HR 0.202,95%CI 0.08-0.51,P=0.001)中证实了生存获益。

结论

MFT 护理可以降低 80 岁以上髋部骨折患者的一年死亡率。这一发现应在多中心随机对照试验中得到验证和扩展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e95f/11238416/ed3d4db4cdc8/12877_2024_5183_Fig1_HTML.jpg

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