Department of Physiology and Pharmacology/Toxicology, Division of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Harm Reduct J. 2024 Jul 10;21(1):131. doi: 10.1186/s12954-024-01048-0.
BACKGROUND: Harm reduction is a crucial approach in addressing the multifaceted challenges of injectable drug use. This paper presents an analysis and mapping of the existing literature on harm reduction research in the context of injectable drug use. By reviewing a comprehensive set of scholarly articles, this study identifies research hotspots, knowledge gaps, and future directions in the field. The findings provide valuable insights for researchers, policymakers, and practitioners to guide future research efforts and inform evidence-based harm reduction interventions. METHODS: Data for the study was obtained from the Scopus database, using keywords and phrases related to harm reduction and injectable drug use. Validation methods were employed to verify the accuracy and comprehensiveness of the search strategy. Data analysis involved identifying growth patterns, key contributors, mapping frequent terms, identifying research hotspots, and identifying emerging research directions. RESULTS: A total of 971 articles were found, with a notable increase from 2015 to 2022. The International Journal of Drug Policy (n = 172, 17.7%) and the Harm Reduction Journal (n = 104, 10.7%) were the most prolific journals, and the United States (n = 558, 57.5%) had the highest number of publications. The Johns Hopkins University (n = 80, 8.5%) was the most prolific institution. Mapping of frequent author keywords revealed the main keywords, including harm reduction, HIV, hepatitis C, and opioid overdose. The highly cited articles cover a broad time span and focus on topics like naloxone distribution, HIV and hepatitis C transmission, while recent articles concentrate on emerging issues such as the impact of the COVID-19 pandemic, fentanyl-related concerns, stigma reduction, and needle and syringe programs. Both sets of articles share a common focus on harm reduction strategies, but recent publications highlight current challenges and developments in the field. CONCLUSIONS: This study provides insights into research landscape on harm reduction in injectable drug use. Research is concentrated in high-income countries, emphasizing the need for more research in low- and middle-income countries. Recent publications focus on emerging challenges like COVID-19 and fentanyl. Research gaps highlight the need for studies in diverse populations, social determinants, program evaluation, and implementation strategies to enhance harm reduction interventions.
背景：在应对注射吸毒带来的多方面挑战方面，减少伤害是一种至关重要的方法。本文分析和绘制了关于注射吸毒背景下减少伤害研究的现有文献，通过审查一整套学术文章，确定了该领域的研究热点、知识空白和未来方向。研究结果为研究人员、政策制定者和从业者提供了有价值的见解，以指导未来的研究工作并为基于证据的减少伤害干预措施提供信息。
方法：本研究的数据来自 Scopus 数据库，使用与减少伤害和注射吸毒相关的关键词和短语。采用验证方法来验证搜索策略的准确性和全面性。数据分析包括确定增长模式、主要贡献者、绘制频繁术语、确定研究热点和识别新兴研究方向。
结果：共发现 971 篇文章，从 2015 年到 2022 年有显著增加。《国际药物政策杂志》（n=172，17.7%）和《减少伤害杂志》（n=104，10.7%）是最有影响力的期刊，美国（n=558，57.5%）发表的文章数量最多。约翰霍普金斯大学（n=80，8.5%）是最有影响力的机构。频繁作者关键词的映射揭示了主要关键词，包括减少伤害、艾滋病毒、丙型肝炎和阿片类药物过量。高引文章涵盖了广泛的时间跨度，重点关注纳洛酮分布、艾滋病毒和丙型肝炎传播等主题，而最近的文章则集中在新冠肺炎大流行、芬太尼相关问题、减少污名化和针具交换计划等新出现的问题上。这两组文章都共同关注减少伤害策略，但最近的出版物强调了该领域当前的挑战和发展。
结论：本研究深入了解了注射吸毒背景下减少伤害研究的现状。研究集中在高收入国家，强调需要在低收入和中等收入国家开展更多研究。最近的出版物侧重于新冠肺炎大流行和芬太尼等新出现的挑战。研究空白突出表明需要在不同人群、社会决定因素、方案评估和实施策略方面开展研究，以加强减少伤害干预措施。
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