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宗教/精神信仰与行为和英格兰西南部一项前瞻性队列研究(ALSPAC)中研究参与情况之间的关联。

The associations between religious/spiritual beliefs and behaviours and study participation in a prospective cohort study (ALSPAC) in Southwest England.

作者信息

Morgan Jimmy, Halstead Isaac, Northstone Kate, Major-Smith Daniel

机构信息

Centre for Academic Child Health, Population Health Sciences, University of Bristol, Bristol, UK.

Population Health Sciences, University of Bristol, Bristol, UK.

出版信息

Wellcome Open Res. 2024 Jun 27;7:186. doi: 10.12688/wellcomeopenres.17975.2. eCollection 2022.

Abstract

BACKGROUND

Longitudinal studies are key to understanding risk factors for health, well-being, and disease, yet associations may be biased if study invitation and participation are non-random. Religious/spiritual beliefs and behaviours (RSBB) are increasingly recognised as having potentially important relationships with health. However, it is unclear whether RSBB is associated with study participation. We examine whether RSBB is associated with participation in the longitudinal birth cohort ALSPAC (Avon Longitudinal Study of Parents and Children).

METHODS

Three RSBB factors were used: religious belief (belief in God/a divine power; yes/not sure/no), religious affiliation (Christian/none/other), and religious attendance (frequency of attendance at a place of worship). Participation was measured in three ways: i) total number of questionnaires/clinics completed (linear and ordinal models); ii) completion of the most recent questionnaire (logistic model); and iii) length of participation (survival model). Analyses were repeated for the ALSPAC mothers, their partners, and the study children, and were adjusted for relevant socio-demographic confounders.

RESULTS

Religious attendance was positively associated with participation in all adjusted models in all three cohorts. For example, study mothers who attended a place of worship at least once a month on average completed two more questionnaires (out of a possible 50), had 50% greater odds of having completed the most recent questionnaire, and had 25% reduced risk of drop-out, relative to those who did not attend. In the adjusted analyses, religious belief and attendance were not associated with participation. However, the majority of unadjusted models showed associations between RSBB and participation.

CONCLUSION

After adjusting for confounders, religious attendance - not religious belief or affiliation - was associated with participation in ALSPAC. These results indicate that use of RSBB variables (and religious attendance in particular) may result in selection bias and spurious associations; these potential biases should be explored and discussed in future studies using these data.

摘要

背景

纵向研究是了解健康、幸福和疾病风险因素的关键,但如果研究邀请和参与是非随机的,关联可能会有偏差。宗教/精神信仰与行为(RSBB)与健康的潜在重要关系越来越受到认可。然而,尚不清楚RSBB是否与研究参与有关。我们研究RSBB是否与参与纵向出生队列研究“埃文亲子纵向研究(ALSPAC)”有关。

方法

使用了三个RSBB因素:宗教信仰(相信上帝/神圣力量;是/不确定/否)、宗教归属(基督教/无/其他)和宗教活动参与度(参加宗教场所的频率)。参与度通过三种方式衡量:i)完成的问卷/诊所总数(线性和有序模型);ii)完成最近一份问卷的情况(逻辑模型);iii)参与时长(生存模型)。对ALSPAC的母亲、她们的伴侣和研究儿童重复进行分析,并对相关社会人口学混杂因素进行调整。

结果

在所有三个队列的所有调整模型中,宗教活动参与度与参与呈正相关。例如,平均每月至少参加一次宗教场所活动的研究母亲,相对于未参加的母亲,平均多完成两份问卷(可能的50份问卷中),完成最近一份问卷的几率高出50%,退出风险降低25%。在调整分析中,宗教信仰和宗教活动参与度与参与无关。然而,大多数未调整模型显示RSBB与参与之间存在关联。

结论

在调整混杂因素后,与参与ALSPAC相关的是宗教活动参与度,而非宗教信仰或宗教归属。这些结果表明,使用RSBB变量(尤其是宗教活动参与度)可能会导致选择偏差和虚假关联;在未来使用这些数据的研究中,应探讨和讨论这些潜在偏差。

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