Center for Infertility and Reproductive Surgery, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St., Boston, MA, 02115, USA.
Department of Environment Health, Harvard T.H. Chan School of Public Health, 75 Francis St., Boston, MA, 02115, USA.
J Assist Reprod Genet. 2024 Sep;41(9):2327-2336. doi: 10.1007/s10815-024-03194-7. Epub 2024 Jul 11.
In 2015, assisted reproductive technology (ART) accounted for 1.7% of all U.S. births, donor eggs accounted for over 17,000 started cycles in 2015, and donor sperm accounting for 6.2% of all cycles started in 2014. With increasing utilization of donor gametes as a method of assisting patients with infertility, the number of babies born each year utilizing gamete donation will also continue to increase. This study aimed to elucidate factors impacting decision to donate, amongst a representative national population.
A survey was distributed via the internet utilizing SurveyMonkey Enterprise with HIPAA compliance. Univariate regressions and frequencies were conducted between each demographic and personal characteristic and the willingness to donate. Log Binomial and linear regression was used categorical and continuous variables, and Risk ratios were calculated.
In this large survey study, 64% of men and 50% of women reported they would be willing to donate gametes, with the majority desiring monetary compensation. Men with a high Consumer Financial Protection Bureau score were less likely to report that they would consider donating sperm compared to a medium high CFPB score. No other financial indicators were associated with considering donating sperm. There were no associations between CFPB score and egg donation outcomes. Black or African American women were less likely to consider donating their eggs compared to other groups, and more likely to desire > $5000 in compensation.
In this large survey study, a small minority of participants reported they would be willing to donate to an unknown infertility patient for reproductive purposes. High and very high CFPB scores were associated with willingness to donate games, but not with desire for monetary compensation or amount.
2015 年,辅助生殖技术(ART)占美国总出生数的 1.7%,当年供卵者周期数超过 17000 个,而供精者周期数占 2014 年总周期数的 6.2%。随着越来越多的患者选择使用供精/卵来辅助生育,每年通过配子捐赠出生的婴儿数量也将继续增加。本研究旨在阐明在具有代表性的全国人群中,影响捐赠决策的因素。
通过 SurveyMonkey Enterprise 互联网平台以 HIPAA 合规的方式发放调查问卷。对每个人口统计学和个人特征与捐赠意愿之间进行单变量回归和频率分析。采用对数二项式和线性回归对分类和连续变量进行分析,并计算风险比。
在这项大型调查研究中,64%的男性和 50%的女性表示愿意捐赠配子,其中大多数人希望获得经济补偿。消费者金融保护局评分较高的男性与评分中高的男性相比,报告称他们更有可能考虑捐赠精子。其他财务指标与考虑捐赠精子无关。消费者金融保护局评分与卵子捐赠结果之间无关联。与其他群体相比,黑人和非裔美国女性更不愿意考虑捐赠卵子,而她们更希望获得超过 5000 美元的补偿。
在这项大型调查研究中,少数参与者表示愿意为生殖目的向未知的不孕患者捐赠配子。高和非常高的消费者金融保护局评分与捐赠配子的意愿相关,但与经济补偿的需求或金额无关。