INTEGRIS-IPF: A New Hope for Tomorrow.
作者信息
Wang Faping, Zhu Min, Luo Fengming
机构信息
Department of Pulmonary and Critical Care Medicine.
State Key Laboratory of Respiratory Health and Multimorbidity.
出版信息
Am J Respir Crit Care Med. 2024 Aug 15;210(4):374-375. doi: 10.1164/rccm.202407-1295ED.
Abstract
摘要
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本文引用的文献
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Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Clinical Trial.贝索特格拉斯特治疗特发性肺纤维化患者：INTEGRIS-IPF 临床试验。
Am J Respir Crit Care Med. 2024 Aug 15;210(4):424-434. doi: 10.1164/rccm.202403-0636OC.
2
Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults.美国成年人中种族和民族对肺纤维化结局的评估。
JAMA Netw Open. 2023 Mar 1;6(3):e232427. doi: 10.1001/jamanetworkopen.2023.2427.
3
Gender and racial equity in clinical research for idiopathic pulmonary fibrosis: a systematic review and meta-analysis.特发性肺纤维化临床研究中的性别和种族公平性：一项系统评价和荟萃分析。
Eur Respir J. 2022 Mar 3;59(3). doi: 10.1183/13993003.02969-2021. Print 2022 Mar.
4
Emerging therapeutic opportunities for integrin inhibitors.整合素抑制剂的新兴治疗机会。
Nat Rev Drug Discov. 2022 Jan;21(1):60-78. doi: 10.1038/s41573-021-00284-4. Epub 2021 Sep 17.
5
Diagnostic and Prognostic Biomarkers for Chronic Fibrosing Interstitial Lung Diseases With a Progressive Phenotype.具有进行性表型的慢性纤维化间质性肺疾病的诊断和预后生物标志物
Chest. 2020 Aug;158(2):646-659. doi: 10.1016/j.chest.2020.03.037. Epub 2020 Apr 5.
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Circulating Plasma Biomarkers of Progressive Interstitial Lung Disease.进行性间质性肺病的循环血浆生物标志物
Am J Respir Crit Care Med. 2020 Jan 15;201(2):250-253. doi: 10.1164/rccm.201907-1343LE.
7
The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.αvβ1整合素在组织纤维化的体内过程中发挥着关键作用。
Sci Transl Med. 2015 May 20;7(288):288ra79. doi: 10.1126/scitranslmed.aaa5094.
8
αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease.αvβ6 整合素可能是间质性肺疾病的一个潜在预后生物标志物。
Eur Respir J. 2015 Aug;46(2):486-94. doi: 10.1183/09031936.00210414. Epub 2015 Mar 5.
9
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.靶向 αv 整合素鉴定出一个核心分子途径，该途径调节几个器官的纤维化。
Nat Med. 2013 Dec;19(12):1617-24. doi: 10.1038/nm.3282. Epub 2013 Nov 10.
10
Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis.整合素介导的转化生长因子β激活在肺纤维化发病机制中的作用
Biochem Soc Trans. 2009 Aug;37(Pt 4):849-54. doi: 10.1042/BST0370849.
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