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全麻对正颌手术术后并发症的影响:全凭静脉麻醉与挥发性麻醉的回顾性比较。

Impact of general anesthesia on postoperative complications in orthognathic surgery: a retrospective comparison of total intravenous anesthesia versus volatile anesthesia.

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.

Department of Anesthesiology, Saga Medical Center Koseikan, 400, Nakabaru, Kasemachi, Saga, Japan.

出版信息

Sci Rep. 2024 Jul 12;14(1):16075. doi: 10.1038/s41598-024-66926-w.

Abstract

Orthognathic surgery has a high incidence of postoperative nausea (PON) and vomiting (POV), delaying mobility initiation and postoperative recovery. Bleeding is another risk associated with this surgical procedure. We aimed to compare total intravenous anesthesia (TIVA) and volatile anesthesia in patients undergoing orthognathic surgery in terms of postoperative nausea and vomiting (PONV) incidence and hemodynamic changes. This retrospective study included 82 patients who underwent bilateral sagittal split ramus osteotomies at Saga University Hospital between April 2016 and April 2021. We compared the effects of TIVA and volatile anesthesia on PONV onset after surgery, acute postoperative hemodynamic changes (blood pressure and heart rate), and factors contributing to PONV. PON was significantly lower in the TIVA group than in the volatile anesthesia group. The total dose of fentanyl contributed to the onset of POV, while the onset of PON was associated with low volumes of fluid infusion and urine in the TIVA and volatile anesthesia groups, respectively. Furthermore, post-extubation hemodynamic change was significantly smaller in the TIVA group than in the volatile anesthesia group. Therefore, TIVA could have a reduced risk of PONV and hemodynamic changes in patients undergoing orthognathic surgery. Employing TIVA could mitigate perioperative complications and enhance patient safety.

摘要

正颌手术术后恶心(PON)和呕吐(POV)的发生率较高,会延迟患者的活动能力恢复。出血是该手术相关的另一个风险。我们旨在比较全身静脉麻醉(TIVA)和挥发性麻醉在正颌手术患者中的术后恶心和呕吐(PONV)发生率和血液动力学变化。本回顾性研究纳入了 2016 年 4 月至 2021 年 4 月在佐贺大学医院接受双侧矢状劈开下颌骨截骨术的 82 例患者。我们比较了 TIVA 和挥发性麻醉对术后 PONV 发作、急性术后血液动力学变化(血压和心率)以及导致 PONV 的因素的影响。TIVA 组 PON 的发生率明显低于挥发性麻醉组。芬太尼的总剂量与 POV 的发作有关,而 TIVA 和挥发性麻醉组中 PON 的发作与液体输注量低和尿量低有关。此外,TIVA 组拔管后血流动力学变化明显小于挥发性麻醉组。因此,TIVA 可能降低正颌手术患者 PONV 和血液动力学变化的风险。使用 TIVA 可以减轻围手术期并发症,提高患者安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/012f/11239665/2f8b0e367b2d/41598_2024_66926_Fig1_HTML.jpg

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