Rittenhouse Dan, Daly Alexander
Pediatrics, Penn State College of Medicine, Hershey, USA.
Pediatrics, Penn State Health Children's Hospital, Hershey, USA.
Cureus. 2024 Jun 10;16(6):e62101. doi: 10.7759/cureus.62101. eCollection 2024 Jun.
Scurvy is a rare diagnosis in resource-rich countries, but cases have been documented in the United States in special populations of pediatric patients at increased risk of micronutrient deficiency such as those with autism spectrum disorder, developmental delay, or eating disorders. We discuss a seven-year-old female with autism spectrum disorder who presented with a limp and refusal to ambulate and elevated inflammatory markers on initial laboratory evaluation. Given her highly selective diet and malnutrition, we made a provisional diagnosis of scurvy and started treatment-dose vitamin C, which led to a significant improvement in her ambulatory function. Plasma vitamin C was ultimately undetectable. She was discharged with vitamin C supplementation and referred to a feeding clinic to address her malnutrition and selective eating.
在资源丰富的国家，坏血病是一种罕见的诊断，但在美国，已记录到在微量营养素缺乏风险增加的儿科特殊人群中出现坏血病病例，如患有自闭症谱系障碍、发育迟缓或饮食失调的儿童。我们讨论了一名患有自闭症谱系障碍的七岁女性，她最初因跛行、拒绝行走以及实验室检查时炎症指标升高前来就诊。鉴于她高度挑食和营养不良，我们初步诊断为坏血病，并开始给予治疗剂量的维生素C，这使她的行走功能有了显著改善。最终检测不到血浆维生素C。她出院时补充了维生素C，并被转介到一家喂养诊所，以解决她的营养不良和挑食问题。
