培高利特治疗帕金森病：一项双盲、安慰剂对照研究。
Pergolide therapy in Parkinson's disease: a double-blind, placebo-controlled study.
作者信息
Sage J I, Duvoisin R C
出版信息
Clin Neuropharmacol. 1985;8(3):260-5. doi: 10.1097/00002826-198509000-00006.
Abstract
A double-blind, placebo-controlled study was conducted of pergolide as an adjunctive treatment to levodopa in 17 patients with advanced Parkinson's disease. There was a significant improvement (p less than 0.05) in total disability score, in gait, and in "wearing off" and "on-off" phenomena. Pergolide is a useful drug in patients with advanced Parkinson's disease.
摘要
对17例晚期帕金森病患者进行了一项双盲、安慰剂对照研究，以评估培高利特作为左旋多巴辅助治疗药物的效果。结果显示，患者的总残疾评分、步态以及“剂末现象”和“开关现象”均有显著改善（p<0.05）。培高利特对晚期帕金森病患者是一种有效的药物。
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