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移植肾动脉狭窄的经皮腔内介入治疗：一项病例系列研究。

Percutaneous transluminal interventions of transplant renal artery stenosis: A case series study.

作者信息

Ghareeb Amjad, Alhamid Naji, Hassan Qussai, Nahas Mohammed Ali

机构信息

Faculty of Medicine, Damascus University, Damascus, Syria.

Nephrology Department, Kidney Surgical Hospital in Damascus, Syria.

出版信息

Ann Med Surg (Lond). 2022 Apr 5;77:103563. doi: 10.1016/j.amsu.2022.103563. eCollection 2022 May.

DOI:10.1016/j.amsu.2022.103563
PMID:35432989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9006739/
Abstract

INTRODUCTION

and importance: Transplant renal artery stenosis (TRAS) is a well-recognized vascular complication after kidney transplant that can lead to graft loss, when it is diagnosed early and treated appropriately it may prevent kidney damage and related systemic squeals.

CASE PRESENTATION

This case-series represents our center experience in managing TRAS using percutaneous transluminal angioplasty [either balloon angioplasty (PTA) or stent placement (PTAS)] in 11 patients.

CLINICAL DISCUSSION

All treated patients experienced immediate total recovery of renal function and normalization of arterial blood pressure without any drug or reducing the number of drugs used; no complications related to the intervention were reported.

CONCLUSION

PTA or PTAS of TRAS can be considered safe and effective when it diagnosed and treated early.

摘要

引言

及重要性：移植肾动脉狭窄（TRAS）是肾移植后一种公认的血管并发症，可导致移植肾丢失，若早期诊断并适当治疗，可能预防肾脏损害及相关全身症状。

病例报告

本病例系列展示了我们中心使用经皮腔内血管成形术[球囊血管成形术（PTA）或支架置入术（PTAS）]治疗11例TRAS患者的经验。

临床讨论

所有接受治疗的患者肾功能立即完全恢复，动脉血压正常，无需任何药物或减少所用药物数量；未报告与干预相关的并发症。

结论

早期诊断并治疗TRAS时，PTA或PTAS可被认为是安全有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/58916dc01477/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/0098b4573882/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/0dd9a432e296/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/58916dc01477/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/0098b4573882/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/0dd9a432e296/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5f/9006739/58916dc01477/gr3.jpg

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An enormous arteriovenous malformation presenting in a child in sacro-gluteal region and managed successfully by recurrent embolisation and surgery.一名儿童骶臀区域出现巨大动静脉畸形，经反复栓塞和手术成功治疗。
Int J Surg Case Rep. 2020;71:244-249. doi: 10.1016/j.ijscr.2020.05.010. Epub 2020 May 23.
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Interventional Therapy for Transplant Renal Artery Stenosis Is Safe and Effective in Preserving Allograft Function and Improving Hypertension.
介入治疗移植肾动脉狭窄在保护移植肾功能和改善高血压方面安全有效。
Vasc Endovascular Surg. 2017 Jan;51(1):4-11. doi: 10.1177/1538574416682157. Epub 2016 Dec 19.
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A Systematic Review of Outcomes Following Percutaneous Transluminal Angioplasty and Stenting in the Treatment of Transplant Renal Artery Stenosis.经皮腔内血管成形术和支架置入术治疗移植肾动脉狭窄的疗效系统评价
Cardiovasc Intervent Radiol. 2015 Dec;38(6):1573-88. doi: 10.1007/s00270-015-1134-z. Epub 2015 Jun 19.
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Transplant renal artery stenosis: clinical manifestations, diagnosis and therapy.移植肾动脉狭窄：临床表现、诊断与治疗。
Clin Kidney J. 2015 Feb;8(1):71-8. doi: 10.1093/ckj/sfu132. Epub 2014 Dec 9.
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Postanastomotic transplant renal artery stenosis: association with de novo class II donor-specific antibodies.移植肾动脉吻合口后狭窄：与新出现的 II 类供体特异性抗体有关。
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