Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee, USA.
J Pediatric Infect Dis Soc. 2024 Jul 12;13(Supplement_2):S125-S130. doi: 10.1093/jpids/piae049.
This review article will summarize the vaccines and monoclonal antibodies currently under evaluation for the prevention of RSV disease in older infants, toddlers and young children. We will review the rationale for passive protection during the first months of life, and the role of active immunization afterwards, either with live attenuated, protein-based or mRNA vaccines.
这篇综述文章将总结目前正在评估的用于预防年长婴儿、幼儿和幼童 RSV 疾病的疫苗和单克隆抗体。我们将回顾在生命的最初几个月被动保护的原理，以及随后使用活减毒、基于蛋白或 mRNA 疫苗进行主动免疫的作用。
