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社会网络构成对认知能力下降的影响:巴伐利亚数字痴呆症登记处(digiDEM Bayern)。

Impact of social network composition on cognitive decline: Digital Dementia Registry Bavaria (digiDEM Bayern).

机构信息

Interdisciplinary Center for Health Technology Assessment (HTA) and Public Health (IZPH), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Center for Health Services Research in Medicine, Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

出版信息

PLoS One. 2024 Jul 12;19(7):e0306447. doi: 10.1371/journal.pone.0306447. eCollection 2024.

Abstract

BACKGROUND

Currently, there is no curative treatment for dementia. The implementation of preventive measures is of great importance. Therefore, it is necessary to identify and address individual and modifiable risk factors. Social isolation, defined through social networks, is a factor that may influence the onset and progression of the disease. The networks of older people are mostly composed of either family or friends. The aim of this study is to examine the influence of social isolation and network composition on cognition over the course of 12 months in people with cognitive impairment.

METHODS

Data basis is the multicentre, prospective, longitudinal register study 'Digital Dementia Registery Bavaria-digiDEM Bayern'. The degree of social isolation was assessed using the Lubben Social Network Scale- Revised (LSNS-R) and the degree of cognitive impairment using the Mini Mental State Examination (MMSE), conducted at baseline and after 12 months. Data were analysed using pre-post ANCOVA, adjusted for baseline MMSE, age, gender, education, living situation and Barthel-Index.

RESULTS

106 subjects (78.9 ± 8.2 years; 66% female) were included in the analysis. The mean MMSE score at baseline was 24.3 (SD = 3.6). Within the friendship subscore, risk for social isolation was highly prevalent (42.5%). Though, there was no difference between individuals with higher/ lower risk of social isolation within the friendship-network after adjusting for common risk factors in cognitive decline over time, F (1,98) = .046, p = .831, partial η2 = .000.

CONCLUSION

The results of this study showed that the risk of social isolation from friends is very high among people with cognitive impairment. However, social isolation does not appear to have a bearing influence on the course of cognition. Nevertheless, it is important for people with cognitive impairment to promote and maintain close social contacts with friends.

摘要

背景

目前,痴呆症尚无治愈方法。实施预防措施非常重要。因此,有必要识别和解决个体和可改变的危险因素。社会隔离是通过社交网络定义的,是影响疾病发生和进展的因素之一。老年人的网络大多由家庭或朋友组成。本研究旨在研究社会隔离和网络构成对认知障碍患者 12 个月内认知的影响。

方法

数据基础是多中心、前瞻性、纵向注册研究“数字痴呆登记巴伐利亚- digiDEM 拜仁”。使用 Lubben 社交网络量表修订版(LSNS-R)评估社会隔离程度,使用 Mini 精神状态检查(MMSE)评估认知障碍程度,在基线和 12 个月后进行。使用预-后 ANCOVA 分析数据,调整基线 MMSE、年龄、性别、教育、生活状况和巴氏指数。

结果

共纳入 106 名受试者(78.9 ± 8.2 岁;66%为女性)进行分析。基线时 MMSE 的平均得分为 24.3(SD = 3.6)。在友谊子量表中,社会隔离的风险很高(42.5%)。然而,在调整共同认知衰退风险因素后,高/低社交隔离风险个体在友谊网络中的差异无统计学意义,F(1,98)=.046,p =.831,部分η 2 =.000。

结论

本研究结果表明,认知障碍患者与朋友的社交隔离风险非常高。然而,社交隔离似乎对认知的发展没有影响。尽管如此,对于认知障碍患者来说,促进和维持与朋友的密切社交联系仍然很重要。

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