Department of Endocrinology, Gender Identity Clinic, Tavistock & Portman NHS Foundation Trust, London, UK.
Department of Endocrinology, Gender Identity Clinic, Tavistock & Portman NHS Foundation Trust, London, UK; St George's University of London Medical School, UK.
Best Pract Res Clin Endocrinol Metab. 2024 Sep;38(5):101908. doi: 10.1016/j.beem.2024.101908. Epub 2024 Jun 25.
Testosterone therapy is the main hormonal treatment offered in transmen to alleviate somatic gender dysphoria. Testosterone can be administered via topical or injectable preparations to achieve physical changes resulting in masculinisation and improve quality of life for the treated individuals. The aim of our paper is to outline methods for testosterone replacement, their impact on main body systems of transmen, potential associated health risks and long term follow up. Androgen use in transgender medicine is safe with appropriate endocrine guidance and monitoring. Studies with longer follow-up period, including those who may prefer low dose testosterone, interested in pregnancy or older people may further improve the management of female-to-male transgender persons.
睾丸酮治疗是跨性别男性缓解躯体性别焦虑的主要激素治疗方法。睾丸酮可以通过局部或注射制剂进行给药，以实现身体的变化，从而使男性化，并改善治疗个体的生活质量。我们的论文旨在概述睾丸酮替代的方法、其对跨性别男性主要身体系统的影响、潜在的相关健康风险和长期随访。在适当的内分泌指导和监测下，雄激素在跨性别医学中的使用是安全的。具有更长随访期的研究，包括那些可能更喜欢低剂量睾丸酮、对怀孕感兴趣或老年人的研究，可能会进一步改善女性向男性跨性别者的管理。
