Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Department of Family Medicine, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.
Nutrients. 2024 Jul 8;16(13):2167. doi: 10.3390/nu16132167.
Elevated uric acid levels are linked with obesity and diabetes. Existing research mainly examines the relationship between sugar-sweetened carbonated beverage (SSB) consumption and uric acid levels. This study explored the association between the quantity and frequency of SSB consumption and elevated uric acid levels in Korean adults. Data from 2881 participants aged 19-64 years (1066 men and 1815 women) in the 2016 Korea National Health and Nutrition Examination Survey were analyzed. Serum uric acid levels were categorized into quartiles, with the highest defined as high uric acid (men, ≥6.7 mg/dL; women, ≥4.8 mg/dL). SSB consumption was classified into quartiles (almost never, <1 cup (<200 mL), 1-3 cups (200-600 mL), ≥3 cups (≥600 mL)) and frequency into tertiles (almost never, ≤1/week, ≥2/week). Multivariate logistic regression assessed the association, with separate analyses for men and women. Increased daily SSB consumption and frequency were significantly associated with high uric acid levels in men but not in women. After adjusting for sociodemographic and health characteristics, consuming ≥3 cups (≥600 mL) of SSBs per day and SSBs ≥ 2/week were significantly associated with high serum uric acid levels in men, but this association was not observed in women. The study concludes that increased SSB intake is linked to elevated uric acid levels in Korean men, but not in women.
尿酸水平升高与肥胖和糖尿病有关。现有研究主要考察了含糖碳酸饮料(SSB)消费与尿酸水平之间的关系。本研究探讨了 SSB 消费的数量和频率与韩国成年人尿酸水平升高之间的关联。对 2016 年韩国全国健康和营养检查调查中 2881 名年龄在 19-64 岁的参与者(男性 1066 人,女性 1815 人)的数据进行了分析。血清尿酸水平分为四组,最高组定义为高尿酸(男性≥6.7mg/dL;女性≥4.8mg/dL)。SSB 消费分为四组(几乎从不,<1 杯(<200 毫升),1-3 杯(200-600 毫升),≥3 杯(≥600 毫升))和频率分为三组(几乎从不,每周≤1 次,每周≥2 次)。多变量逻辑回归评估了这种关联,分别对男性和女性进行了分析。男性中,SSB 日消耗量和频率的增加与高尿酸水平显著相关,但在女性中没有这种相关性。在调整了社会人口学和健康特征后,每天饮用≥3 杯(≥600 毫升)SSB 和每周饮用 SSB≥2 次与男性高血清尿酸水平显著相关,但在女性中未观察到这种关联。研究结论是,SSB 摄入量增加与韩国男性尿酸水平升高有关,但与女性无关。