Sleep and Heart Laboratory, Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Recife, Brazil; Graduante Program in Physical Education, Federal University of Pernambuco, Recife, Brazil.
Sleep and Heart Laboratory, Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco, Recife, Brazil; Graduante Program in Physical Education, Federal University of Pernambuco, Recife, Brazil.
Sleep Med. 2024 Sep;121:184-188. doi: 10.1016/j.sleep.2024.07.006. Epub 2024 Jul 9.
This study aimed to verify the effect of 12 weeks of HIIT on the perceived sleep quality and excessive daytime sleepiness in patients with obstructive sleep apnea (OSA). For this, a secondary analysis of a randomized controlled trial, including 36 adults with moderate-severe OSA (19 males; 52.2 ± 9.8 years; body mass index = 34.2 ± 5.8; AHI = 42.0 ± 22.9 e/h) was performed. Participants were randomly assigned to HIIT [5 periods of 4 min of walking or running on a treadmill at 90-95 % of maximum heart rate (HRmax) interspersed with 3 min of walking at 50-55 % of HRmax performed three times per week for 12 weeks] or a control group (CG; stretching exercises performed two times per week for 12 weeks). Specific domains of subjective sleep quality and EDS were assessed at baseline and post 12 weeks. Generalized estimated equation were used to verify between groups and times differences. There were no group × time interactions for the domains sleep duration (0.416), sleep efficiency (0.198), sleep disturbance (0.523), and sleep medications (0.915). However, significant group × time interactions were observed for global sleep score (0.022), and for the domains sleep quality (0.001), sleep latency (0.029), and daytime dysfunction (0.012). In addition, there was a significant group × time interaction for EDS (HIIT = -3.4 ± 0.9; CG change = -1.0 ± 1.0; p = 0.023). Thus, in patients with OSA, 12 weeks of HIIT improves perceived sleep quality and daytime sleepiness.
这项研究旨在验证 12 周高强度间歇训练（HIIT）对阻塞性睡眠呼吸暂停（OSA）患者睡眠质量和日间嗜睡的影响。为此，对一项随机对照试验进行了二次分析，共纳入 36 名中重度 OSA 患者（男性 19 名；52.2±9.8 岁；体重指数 34.2±5.8；呼吸暂停低通气指数 42.0±22.9 次/小时）。参与者被随机分配到 HIIT 组[5 个周期，每个周期 4 分钟在跑步机上行走或跑步，达到最大心率的 90-95%（HRmax），其间穿插 3 分钟以 50-55%HRmax 的速度行走，每周进行 3 次，共 12 周]或对照组（CG；每周进行 2 次拉伸运动，共 12 周）。在基线和 12 周后评估主观睡眠质量和 EDS 的特定领域。使用广义估计方程来验证组间和时间差异。在睡眠持续时间（0.416）、睡眠效率（0.198）、睡眠障碍（0.523）和睡眠药物（0.915）等领域，组间和时间均无交互作用。然而，在整体睡眠评分（0.022）以及睡眠质量（0.001）、睡眠潜伏期（0.029）和日间功能障碍（0.012）等领域，观察到显著的组间和时间交互作用。此外，对于 EDS，也存在显著的组间和时间交互作用（HIIT= -3.4±0.9；CG 变化= -1.0±1.0；p=0.023）。因此，在 OSA 患者中，12 周的 HIIT 可改善睡眠质量和日间嗜睡。
