Kahn J, Anderton B H, Probst A, Ulrich J, Esiri M M
J Neurol Neurosurg Psychiatry. 1985 Sep;48(9):924-6. doi: 10.1136/jnnp.48.9.924.
Neurons undergoing granulovacuolar degeneration have been examined in paraffin sections with three monoclonal antibodies to neurofilaments. Two of these antibodies (BF10, RT97) had been shown previously to react with neurofibrillary tangles. One of these antibodies (RT97) reacted with granular component of granulovacuolar degeneration. BF10 sometimes reacted with the surrounding neuronal cytoplasm. Granulovacuolar degeneration was also detected in a few cells of the anterior olfactory nucleus.
已使用三种抗神经丝单克隆抗体对经历颗粒空泡变性的神经元进行石蜡切片检查。其中两种抗体(BF10、RT97)先前已被证明可与神经原纤维缠结发生反应。其中一种抗体(RT97)与颗粒空泡变性的颗粒成分发生反应。BF10有时与周围的神经元细胞质发生反应。在前嗅核的少数细胞中也检测到了颗粒空泡变性。