Ou Shi-Ping, Liao Xiao-Liang, Huang Zi-Tao, Hu Yan-Cong, Cai Zongwei, Chen Zhi-Feng
Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, School of Environmental Science and Engineering, Guangdong University of Technology, Guangzhou 510006, China.
Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, School of Environmental Science and Engineering, Guangdong University of Technology, Guangzhou 510006, China; State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong 999077, China.
J Environ Sci (China). 2025 Jan;147:282-293. doi: 10.1016/j.jes.2023.12.003. Epub 2023 Dec 9.
There have been reports of potential health risks for people from hydrophobic organic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), polychlorinated hydrocarbons (PCHs), and organophosphate flame retardants (OPFRs). When a contaminated site is used for residential housing or public utility and recreation areas, the soil-bound organic pollutants might pose a threat to human health. In this study, we investigated the contamination profiles and potential risks to human health of 15 PAHs, 6 PCHs, and 12 OPFRs in soils from four contaminated sites in China. We used an in vitro method to determine the oral bioaccessibility of soil pollutants. Total PAHs were found at concentrations ranging from 26.4 ng/g to 987 ng/g. PCHs (0.27‒14.3 ng/g) and OPFRs (6.30‒310 ng/g) were detected, but at low levels compared to earlier reports. The levels of PAHs, PCHs, and OPFRs released from contaminated soils into simulated gastrointestinal fluids ranged from 1.74% to 91.0%, 2.51% to 39.6%, and 1.37% to 96.9%, respectively. Based on both spiked and unspiked samples, we found that the oral bioaccessibility of pollutants was correlated with their logK and molecular weight, and the total organic carbon content and pH of soils. PAHs in 13 out of 38 contaminated soil samples posed potential high risks to children. When considering oral bioaccessibility, nine soils still posed potential risks, while the risks in the remaining soils became negligible. The contribution of this paper is that it corrects the health risk of soil-bound organic pollutants by detecting bioaccessibility in actual soils from different contaminated sites.
已有报告指出，多环芳烃（PAHs）、多氯代烃（PCHs）和有机磷酸酯阻燃剂（OPFRs）等疏水性有机污染物会给人类带来潜在健康风险。当受污染场地被用作住宅、公共设施或娱乐区域时，土壤中的有机污染物可能会对人类健康构成威胁。在本研究中，我们调查了中国四个受污染场地土壤中15种PAHs、6种PCHs和12种OPFRs的污染情况及其对人类健康的潜在风险。我们采用体外方法测定土壤污染物的口服生物可及性。总PAHs浓度范围为26.4 ng/g至987 ng/g。检测到了PCHs（0.27 - 14.3 ng/g）和OPFRs（6.30 - 310 ng/g），但与早期报告相比，含量较低。受污染土壤释放到模拟胃肠液中的PAHs、PCHs和OPFRs水平分别为1.74%至91.0%、2.51%至39.6%和1.37%至96.9%。基于加标和未加标样品，我们发现污染物的口服生物可及性与其logK、分子量以及土壤的总有机碳含量和pH值相关。38个受污染土壤样品中有13个的PAHs对儿童构成潜在高风险。考虑口服生物可及性时，9个土壤仍存在潜在风险，而其余土壤的风险可忽略不计。本文的贡献在于通过检测不同受污染场地实际土壤中的生物可及性来修正土壤中有机污染物的健康风险。
