Howorth P J
J R Army Med Corps. 1985 Jun;131(2):100-4. doi: 10.1136/jramc-131-02-09.
The role of intravenous salt solutions in resuscitation is reviewed historically. A brief account of the pathophysiology of shock is given. The particular use of hypertonic solutions in the resuscitation of severely shocked patients is reviewed and its mechanism of action discussed. It is considered that hypertonic solutions may find a role in any future major military conflict. Two hypertonic solutions that are suggested for consideration in this context are 12% sodium chloride (2 mmol/ml) and 8.4% sodium bicarbonate (1 mmol/ml).
本文回顾了静脉盐溶液在复苏中的作用的历史。简要介绍了休克的病理生理学。综述了高渗溶液在严重休克患者复苏中的特殊应用,并讨论了其作用机制。认为高渗溶液可能在未来的任何重大军事冲突中发挥作用。在此背景下建议考虑的两种高渗溶液是12%氯化钠(2 mmol/ml)和8.4%碳酸氢钠(1 mmol/ml)。