Division of Cancer Sciences, The University of Manchester, Manchester, UK.
The Prevent Breast Cancer Research Unit, The Nightingale Centre, Manchester University NHS Foundation Trust, Manchester, UK.
J Hum Nutr Diet. 2024 Oct;37(5):1170-1185. doi: 10.1111/jhn.13347. Epub 2024 Jul 14.
Breast cancer is the most frequent female malignancy in the UK. Around 20% of cases are linked to weight gain, excess weight and health behaviours. We designed a weight gain prevention, health behaviour intervention for young women at increased risk.
The study comprised a single arm observational study over 2 months testing acceptability and usability of the intervention: online group welcome event, app and private Facebook group. Females aged 18-35 years at moderate or high risk of breast cancer (>17% lifetime risk) were recruited via invite letters and social media posts. The app included behaviour change techniques and education content. Online questionnaires were completed at baseline, as well as at 1 and 2 months. We also assessed feasibility of study procedures.
Both recruitment methods were successful. Thirty-five women were recruited, 26% via social media posts. Median age was 33 (interquartile range = 28.2-34.5) years, the majority (94.1%) were of White ethnicity. Thirty-four participants were included in the analyses, of which 94% downloaded the app. Median self-monitoring logs per participant during the study period was 10.0 (interquartile range = 4.8-28.8). App quality mean (SD) score was 3.7 (0.6) at 1 and 2 months (scale: 1-5). Eighty-nine per cent rated the app at average or above at 1 month and 75.0% at 2 months. Nineteen women (55.9%) joined the Facebook group and there were 61 comments and 83 reactions and votes from participants during the study period.
This first iteration of the app and intervention was well received and is suitable to progress to the next stage of refining and further testing.
乳腺癌是英国最常见的女性恶性肿瘤。大约 20%的病例与体重增加、超重和健康行为有关。我们为处于较高乳腺癌风险的年轻女性设计了一种预防体重增加和改善健康行为的干预措施。
该研究为为期 2 个月的单臂观察性研究，旨在测试干预措施的可接受性和可用性：在线小组欢迎活动、应用程序和私人 Facebook 小组。通过邀请函和社交媒体帖子招募年龄在 18-35 岁、乳腺癌风险中度或高度（终生风险>17%）的女性。应用程序包括行为改变技术和教育内容。参与者在基线、1 个月和 2 个月时完成在线问卷。我们还评估了研究程序的可行性。
两种招募方法均成功。共招募了 35 名女性，其中 26%通过社交媒体帖子招募。中位年龄为 33 岁（四分位间距=28.2-34.5），大多数（94.1%）为白人。34 名参与者纳入分析，其中 94%下载了应用程序。在研究期间，每位参与者的自我监测日志中位数为 10.0（四分位间距=4.8-28.8）。应用程序质量的平均（SD）评分在 1 个月和 2 个月时分别为 3.7（0.6）（评分范围：1-5）。89%的参与者在 1 个月时对应用程序的评价为平均或以上，75.0%的参与者在 2 个月时对应用程序的评价为平均或以上。19 名女性（55.9%）加入了 Facebook 小组，在研究期间，参与者共发表了 61 条评论、83 次反应和投票。
该应用程序和干预措施的首次迭代得到了很好的反馈，适合进入下一阶段的改进和进一步测试。
