Department of Psychology, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK.
Philos Trans R Soc Lond B Biol Sci. 2024 Aug 26;379(1908):20230248. doi: 10.1098/rstb.2023.0248. Epub 2024 Jul 15.
We present novel research on the cortical dynamics of atypical perceptual and emotional processing in people with symptoms of depersonalization-derealization disorder (DP-DR). We used electroencephalography (EEG)/event-related potentials (ERPs) to delineate the early perceptual mechanisms underlying emotional face recognition and mirror touch in adults with low and high levels of DP-DR symptoms (low-DP and high-DP groups). Face-sensitive visual N170 showed markedly less differentiation for emotional versus neutral face-voice stimuli in the high- than in the low-DP group. This effect was related to self-reported bodily symptoms like disembodiment. Emotional face-voice primes altered mirror touch at somatosensory cortical components P45 and P100 differently in the two groups. In the high-DP group, mirror touch occurred only when seeing touch after being confronted with angry face-voice primes. Mirror touch in the low-DP group, however, was unaffected by preceding emotions. Modulation of mirror touch following angry others was related to symptoms of self-other confusion. Results suggest that others' negative emotions affect somatosensory processes in those with an altered sense of bodily self. Our findings are in line with the idea that disconnecting from one's body and self (core symptom of DP-DR) may be a defence mechanism to protect from the threat of negative feelings, which may be exacerbated through self-other confusion. This article is part of the theme issue 'Sensing and feeling: an integrative approach to sensory processing and emotional experience'.
我们提出了关于人格解体-现实解体障碍（DP-DR）患者异常知觉和情感处理的皮质动力学的新研究。我们使用脑电图（EEG）/事件相关电位（ERPs）来描绘具有低水平和高水平 DP-DR 症状（低 DP 和高 DP 组）的成年人中情感面孔识别和镜像触摸的早期知觉机制。与低 DP 组相比，高 DP 组的视觉 N170 对面部敏感的刺激对情感与中性面孔声音的区分明显较少。这种效应与身体症状如脱体有关。在两组中，情感面孔声音启动对体感皮质成分 P45 和 P100 的镜像触摸有不同的影响。在高 DP 组中，只有在看到愤怒的面孔声音启动后才会出现触摸镜像。然而，在低 DP 组中，镜像触摸不受先前情绪的影响。在受到他人愤怒情绪的影响下，镜像触摸的调节与自我他人混淆的症状有关。结果表明，他人的负面情绪会影响那些对身体自我感觉改变的感觉运动过程。我们的发现与这样一种观点一致，即与身体和自我的脱节（DP-DR 的核心症状）可能是一种防御机制，以保护免受负面情绪的威胁，而自我他人混淆可能会加剧这种威胁。本文是主题为“感知和感觉：一种综合的感觉处理和情感体验方法”的一部分。
