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维持性透析患者30天非计划再次入院的预测因素

Predictors of 30-day Unplanned Hospital Readmissions among Maintenance Dialysis Patients.

作者信息

Uy Chicki Florette C, Manalili Sheryll Anne R, Gomez Lynn A

机构信息

Division of Nephrology, Department of Medicine, Philippine General Hospital, University of the Philippines Manila.

出版信息

Acta Med Philipp. 2024 Mar 22;58(5):43-51. doi: 10.47895/amp.vi0.7018. eCollection 2024.

DOI:10.47895/amp.vi0.7018
PMID:39005618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240001/
Abstract

BACKGROUND AND OBJECTIVES

Patients on dialysis are twice as likely to have early readmissions. This study aimed to identify risk factors for 30-day unplanned readmission among patients on maintenance dialysis in a tertiary hospital.

METHODS

We conducted a retrospective, unmatched, case-control study. Data were taken from patients on maintenance hemodialysis admitted in the University of the Philippines-Philippine General Hospital (UP-PGH) between January 2018 and December 2020. Patients with 30-day readmission were included as cases and patients with >30-day readmissions were taken as controls. Multivariable regression with 30-day readmission as the outcome was used to identify significant predictors of early readmission.

RESULTS

The prevalence of 30-day unplanned readmission among patients on dialysis is 36.96%, 95%CI [31.67, 42.48]. In total, 119 cases and 203 controls were analyzed. Two factors were significantly associated with early readmission: the presence of chronic glomerulonephritis [OR 2.35, 95% CI 1.36 to 4.07, p-value=0.002] and number of comorbidities [OR 1.34, 95% CI 1.12 to 1.61, p-value=0.002]. The most common reasons for early readmission are infection, anemia, and uremia/underdialysis.

CONCLUSION

Patients with chronic glomerulonephritis and multiple comorbidities have significantly increased odds of early readmission. Careful discharge planning and close follow up of these patients may reduce early readmissions.

摘要

背景与目的

接受透析治疗的患者再次入院的可能性是正常人的两倍。本研究旨在确定一家三级医院中维持性透析患者30天内非计划再次入院的风险因素。

方法

我们进行了一项回顾性、非匹配病例对照研究。数据取自2018年1月至2020年12月在菲律宾大学菲律宾总医院(UP-PGH)接受维持性血液透析的患者。30天内再次入院的患者作为病例,30天以上再次入院的患者作为对照。以30天再次入院为结果进行多变量回归分析,以确定早期再次入院的显著预测因素。

结果

透析患者30天内非计划再次入院的患病率为36.96%,95%置信区间为[31.67, 42.48]。总共分析了119例病例和203例对照。有两个因素与早期再次入院显著相关:慢性肾小球肾炎的存在[比值比2.35,95%置信区间1.36至4.07,p值=0.002]和合并症数量[比值比1.34,95%置信区间1.12至1.61,p值=0.002]。早期再次入院最常见的原因是感染、贫血和尿毒症/透析不足。

结论

患有慢性肾小球肾炎和多种合并症的患者早期再次入院的几率显著增加。对这些患者进行仔细的出院计划和密切随访可能会减少早期再次入院的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/069150921e3d/AMP-58-5-7018-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/52e09e50acda/AMP-58-5-7018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/a53ff386d267/AMP-58-5-7018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/069150921e3d/AMP-58-5-7018-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/52e09e50acda/AMP-58-5-7018-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/a53ff386d267/AMP-58-5-7018-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b4/11240001/069150921e3d/AMP-58-5-7018-g003.jpg

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本文引用的文献

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Association between the Charlson Comorbidity Index and the risk of 30-day unplanned readmission in patients receiving maintenance dialysis.接受维持性透析患者Charlson 合并症指数与 30 天非计划性再入院风险的关系。
BMC Nephrol. 2019 Oct 7;20(1):363. doi: 10.1186/s12882-019-1538-0.
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全国维持性血液透析患者 30 天内非计划性再入院率的估算。
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