Zhang Tian, Liu Zhutao, Li Na
Affiliated Hospital of Shandong Second Medical University, School of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Front Med (Lausanne). 2024 Jun 28;11:1402396. doi: 10.3389/fmed.2024.1402396. eCollection 2024.
Uveitis refers to a group of ocular inflammatory diseases that can significantly impair vision. Although systemic corticosteroid therapy has shown substantial efficacy in treating uveitis, extensive use of corticosteroids is associated with significant adverse effects. Recently, a biodegradable, sustained-release implant, namely dexamethasone intravitreal implant (Ozurdex), has been reported for treating non-infectious and infectious uveitis. This review aims to summarize the experiences with Ozurdex treatment across various forms of uveitis and to assist readers in understanding the appropriate timing and potential side effects of Ozurdex in uveitis treatment, thereby maximizing patient benefits in uveitis management.
葡萄膜炎是指一组可显著损害视力的眼部炎症性疾病。尽管全身用皮质类固醇疗法在治疗葡萄膜炎方面已显示出显著疗效，但广泛使用皮质类固醇会带来显著的不良反应。最近，一种可生物降解的缓释植入物，即地塞米松玻璃体内植入剂（Ozurdex），已被报道用于治疗非感染性和感染性葡萄膜炎。本综述旨在总结Ozurdex治疗各种类型葡萄膜炎的经验，并帮助读者了解Ozurdex在葡萄膜炎治疗中的合适时机和潜在副作用，从而在葡萄膜炎管理中使患者受益最大化。
