B. P. Koirala Lions Centre for Ophthalmic Studies, Department of Ophthalmology, Maharajgunj Medical Campus, Tribhuvan University, Institute of Medicine, Kathmandu, Nepal.
J Nepal Health Res Counc. 2021 Dec 15;19(3):647-649. doi: 10.33314/jnhrc.v19i3.2292.
Intravitreal steroid implants are the latest trend for uveitis macular oedema treatment. Dexamethasone intravitreal implants are new in our contexts but we report 2 cases of uveitic cystoid macular oedema where this implant proved very useful in the treatment of recalcitrant macular oedema where other treatment modality fails. Two cases of non-infectious uveitis and intermediate uveitis with recalcitrant uveitic macular oedema underwent dexamethasone intravitreal implantation. Their central macular thickness and central macular volume reduced significantly with the implant. With the reduction in macular parameters, the best-corrected visual acuity also improved and visual rehabilitation was achieved. Thus, dexamethasone intravitreal implant helps in sustained drug delivery inside the vitreous leading to resolution of uveitic macular oedema in recalcitrant cases. Keywords: Macular oedema; ozurdex; steroid; uveitis; vision.
玻璃体内类固醇植入物是治疗葡萄膜炎黄斑水肿的最新趋势。地塞米松玻璃体内植入物在我们的环境中是新的，但我们报告了 2 例葡萄膜炎性囊样黄斑水肿病例，其中这种植入物在治疗其他治疗方法失败的顽固性黄斑水肿方面非常有用。2 例非感染性葡萄膜炎和中间葡萄膜炎伴顽固性葡萄膜炎性黄斑水肿患者接受了地塞米松玻璃体内植入物治疗。他们的黄斑中心厚度和黄斑中心体积随着植入物的使用显著降低。随着黄斑参数的降低，最佳矫正视力也得到了提高，实现了视力康复。因此，地塞米松玻璃体内植入物有助于在玻璃体内持续输送药物，从而解决顽固性葡萄膜炎性黄斑水肿问题。关键词：黄斑水肿；Ozurdex；类固醇；葡萄膜炎；视力。
